[1]曹雯,范尧夫,孙洪平,等.逆转2型糖尿病:梦想还是现实?[J].国际内分泌代谢杂志,2020,40(05):315-319.[doi:10.3760/cma.j.cn121383-20191110-11015]
　Cao Wen,Fan Yaofu,Sun Hongping,et al.Reversing type 2 diabetes mellitus: dreams or reality?[J].International Journal of Endocrinology and Metabolism,2020,40(05):315-319.[doi:10.3760/cma.j.cn121383-20191110-11015]
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逆转2型糖尿病:梦想还是现实?()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
40
期数:
2020年05期
页码:
315-319
栏目:
综述
出版日期:
2020-09-20

文章信息/Info

Title:
Reversing type 2 diabetes mellitus: dreams or reality?
作者:
曹雯1; 范尧夫2; 孙洪平2; 胡咏新2; 杨昱1; 赵一璟1; 刘超2; 王昆1
1南京医科大学附属江宁医院内分泌科 211100; 2南京中医药大学附属中西医结合医院内分泌院区 210028
Author(s):
Cao Wen1;  Fan Yaofu2;  Sun Hongping2;  Hu Yongxin2;  Yang Yu1;  Zhao Yijing1;  Liu Chao2;  Wang Kun2
1Department of Endocrinology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China; 2Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China
关键词:
2型糖尿病;  糖尿病逆转;  生活方式干预;  抗糖尿病药物;  代谢手术
Keywords:
Type 2 diabetes mellitus;  Reversal of diabetes mellitus;  Lifestyle modification;  Antidiabetic drugs;  Metabolic surgery
DOI:
10.3760/cma.j.cn121383-20191110-11015
文献标志码:
A
摘要:
目前,国内外权威指南和临床医生对2型糖尿病的治疗大多着眼于控制高血糖,而极少关注采取积极可行的措施促进2型糖尿病的缓解和逆转。早在20世纪60年代,就有学者致力于逆转糖尿病可行性及其机制的研究。逆转糖尿病可以通过四大举措得以实现,包括预防糖尿病前期向糖尿病的转化、基于减重的策略、基于短期强化治疗策略以及基于代谢手术的策略。这些措施均被证明能够有效缓解或逆转本病的发生、发展,这对糖尿病等慢性疾病管理的传统观念提出了挑战,并为糖尿病的合理治疗提供了新的思路。
Abstract:
At present, both guidelines and clinicians for the management of diabetes are mostly focused on the control of hyperglycemia, while very little attention has been paid to positive and feasible measures for promoting the remission or reversal of type 2 diabetes. Back in the 1960s, some scholars studied the feasibility to reverse type 2 diabetes and its mechanisms. It has been found that reversing diabetes can be achieved through four major initiatives, including the prevention of progression from prediabetes to diabetes, strategies based on weight reduction, short-term intensive treatment, and metabolic surgery. The ideas to reverse type 2 diabetes challege the traditional options for the treatment of chronic diseases and provide a brand new direction for reasonable management of diabetes.

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备注/Memo

备注/Memo:
基金项目:江苏省中医药局课题项目(FY201808)
更新日期/Last Update: 2020-09-20