[1]林延艳,赵林双.运动改善糖尿病心肌病的机制[J].国际内分泌代谢杂志,2017,37(03):207-209,216.[doi:10.3760/cma.j.issn.1673-4157.2017.03.017]
 Lin Yanyan,Zhao Linshuang..Mechanisms of exercise in improving diabetic cardiomyopathy[J].International Journal of Endocrinology and Metabolism,2017,37(03):207-209,216.[doi:10.3760/cma.j.issn.1673-4157.2017.03.017]
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运动改善糖尿病心肌病的机制()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年03期
页码:
207-209,216
栏目:
综述
出版日期:
2017-05-20

文章信息/Info

Title:
Mechanisms of exercise in improving diabetic cardiomyopathy
作者:
林延艳赵林双
430070 武汉,广州军区武汉总医院内分泌科
Author(s):
Lin Yanyan Zhao Linshuang.
Department of Endocrinology, Wuhan General Hospital of Guangzhou Military, Wuhan 430070, China
关键词:
运动 糖尿病 糖尿病心肌病
Keywords:
Exercise Diabetes mellitus Diabetic cardiomyopathy
DOI:
10.3760/cma.j.issn.1673-4157.2017.03.017
摘要:
糖尿病心肌病是糖尿病严重的并发症之一,也是糖尿病患者发生猝死的主要原因之一。目前研究显示,运动是改善糖尿病心肌损害的重要的非药物干预措施。它可以通过改善心肌代谢、增强Ca2+调控、保护细胞内线粒体功能等,实现抑制心肌细胞凋亡、心肌微血管病变、心肌纤维化等作用,最终缓解糖尿病并发症的发生、发展。阐述运动对糖尿病心肌的作用机制,可为延缓甚至逆转糖尿病心肌病进展及心肌重构,防止其转变为心功能不全甚至心力衰竭提供新的理论依据。
Abstract:
Diabetic cardiomyopathy is one of the most serious complications of diabetes and the main causes of sudden death in diabetics. Current studies showed that, exercise has been regarded as an efficient non-pharmacological treatment for diabetes, it can inhibit the pathological processes of myocardial apoptosis, myocardial microvascular disease, and myocardial fibrosis through improving myocardial metabolism, enhancing the regulation of Ca2+, and protecting the function of mitochondria in cells, and eventually, alleviating the occurrence and development of diabetic complication. Describing the mechanisms of exercise on diabetic myocardium may provide new theory for alleviating, or even reversing the development of diabetic cardiomyopathy, and prevent it develop to heart failure.

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备注/Memo

备注/Memo:
基金项目:湖北省自然科学基金资助项目(2012FFB06807) 通信作者:赵林双,Email:zls7111@aliyun.com
更新日期/Last Update: 2017-05-20