[1]于晓蕾 陈新卫 任路平.骨形态发生蛋白与非酒精性脂肪性肝病[J].国际内分泌代谢杂志,2018,38(02):128-130.[doi:10.3760/cma.j.issn.1673-4157.2018.02.015]
 Yu Xiaolei*,Chen Xinwei,Ren Luping.Bone morphogenetic protein and non-alcoholic fatty liver disease[J].International Journal of Endocrinology and Metabolism,2018,38(02):128-130.[doi:10.3760/cma.j.issn.1673-4157.2018.02.015]
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骨形态发生蛋白与非酒精性脂肪性肝病()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年02期
页码:
128-130
栏目:
基础研究
出版日期:
2018-03-20

文章信息/Info

Title:
Bone morphogenetic protein and non-alcoholic fatty liver disease
作者:
于晓蕾 陈新卫 任路平
075000 张家口,河北北方学院研究生学院(于晓蕾); 050017石家庄,河北医科大学研究生学院(陈新卫); 050051 石家庄,河北省人民医院内分泌代谢病科(任路平)
Author(s):
Yu Xiaolei* Chen Xinwei Ren Luping
*Graduate School of Hebei North University, Zhangjiakou 075000, China
关键词:
骨形态发生蛋白家族 非酒精性脂肪性肝病 脂代谢
Keywords:
Bone morphogenetic protein family Non-alcoholic fatty liver disease Lipid metabolism
DOI:
10.3760/cma.j.issn.1673-4157.2018.02.015
摘要:
非酒精性脂肪性肝病是目前最常见的慢性肝脏疾病,是肝的代谢障碍表现。近年来研究发现,骨形态发生蛋白(BMP)家族(BMP-9、BMP-7及BMP-6等)与非酒精性脂肪性肝病密切相关,机制涉及铁过载、炎性反应、激活相关蛋白等,其有望成为治疗非酒精性脂肪性肝病的新靶点。
Abstract:
Non-alcoholic fatty liver disease is by far the most common chronic liver disease, is the metabolic disorders of liver. In recent years, studies have found that bone morphogenetic protein(BMP)family(BMP-9, BMP-7, BMP-6 and so on)was closely related to non-alcoholic fatty liver disease,its mechanism involved iron overload, inflammatory response, activation of related proteins and so on. It is expected to be a new target for the treatment of non-alcoholic fatty liver disease.

参考文献/References:


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备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年基金(81200639)
通信作者:任路平,Email:renluping1122@163.com
更新日期/Last Update: 1900-01-01