[1]陈金安 柳岚 蒋克春 王爱萍.糖尿病足溃疡中趋化因子的作用及机制[J].国际内分泌代谢杂志,2015,(05):357-359.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.018]
 Chen Jinan,Liu Lan,Jiang Kechun,et al.Roles of chemokines in diabetic foot ulcer and the mechanisms[J].International Journal of Endocrinology and Metabolism,2015,(05):357-359.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.018]
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糖尿病足溃疡中趋化因子的作用及机制()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年05期
页码:
357-359
栏目:
基础研究
出版日期:
2015-09-20

文章信息/Info

Title:
Roles of chemokines in diabetic foot ulcer and the mechanisms
作者:
陈金安 柳岚 蒋克春 王爱萍
210002 南京,解放军第四五四医院内分泌科,南京军区糖尿病足中心
Author(s):
Chen JinanLiu LanJiang KechunWang Aiping.
Department of Endocrinology, The 454th Hospital of PLA, The Central of Diabetic Foot in Nanjing Military Command, Nanjing 210002,China
关键词:
趋化因子 糖尿病 足溃疡
Keywords:
Chemokines Diabetes mellitus Foot ulcers
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.05.018
摘要:
糖尿病足溃疡(DFUs)是糖尿病患者常见的慢性并发症之一,有感染、神经和(或)血管病变、愈合障碍等病理生理学特点。趋化因子具有免疫调节、趋化等作用,与DFUs的关系仍不清楚。它可能通过介导炎性细胞、血管平滑肌细胞、内皮祖细胞、上皮细胞,参与DFUs的炎性反应、动脉粥样斑块形成、新生血管生成和组织修复等过程。探讨趋化因子在DFUs中的作用,可为DFUs的治疗提供可能的新方法。
Abstract:
Diabetic foot ulcer is one of the most common chronic complications of diabetes. Infection, nerve and/or vascular lesions, and healing impairment are common pathophysiologic characteristics of diabetic foot ulcer. Chemokines play roles in immune regulation, chemotaxis and catalytic, but their roles in diabetic foot ulcer are still unclear. They may play roles in inflammatory response, atherosclerosis, angiogenesis as well as wound healing by acting on inflammatory cells, vascular smooth muscle cells, endothelial progenitor cells and epithelial cells. Further researches on the role of chemokines in diabetic foot ulcer may provide new direction for the treatment of diabetic foot ulcers.

参考文献/References:

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备注/Memo

备注/Memo:
作者单位:210002 南京,解放军第四五四医院内分泌科,南京军区糖尿病足中心 通信作者:王爱萍,Email:wap454hospital@163.com
更新日期/Last Update: 2015-09-20