[1]周华梅,吴晓颖,张毅.十二指肠黏膜表面重建术治疗2型糖尿病的研究进展[J].国际内分泌代谢杂志,2022,42(02):146-149.[doi:10.3760/cma.j.cn121383-20201123-11049]
 Zhou Huamei,Wu Xiaoying,Zhang Yi..Treatment of duodenal mucosal surface reconstruction in type 2 diabetes mellitus patients[J].International Journal of Endocrinology and Metabolism,2022,42(02):146-149.[doi:10.3760/cma.j.cn121383-20201123-11049]
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十二指肠黏膜表面重建术治疗2型糖尿病的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年02期
页码:
146-149
栏目:
综述
出版日期:
2022-03-20

文章信息/Info

Title:
Treatment of duodenal mucosal surface reconstruction in type 2 diabetes mellitus patients
作者:
周华梅1吴晓颖2张毅1
1重庆市南川区人民医院内分泌科 408400; 2重庆市綦江区人民医院消化内科 401420
Author(s):
Zhou Huamei1 Wu Xiaoying2 Zhang Yi1.
1Department of Endocrinology, the People's Hospital of Nanchuan District, Chongqing 408400, China; 2Department of Gastroenterology, the People's Hospital of Qijiang District, Chongqing 401420, China
关键词:
十二指肠黏膜表面重建术 糖尿病 疗效
Keywords:
Duodenal mucosal resurfacing Diabetes Treatment effect
DOI:
10.3760/cma.j.cn121383-20201123-11049
摘要:
2型糖尿病目前主要采用饮食、运动和药物相结合的方法进行治疗,但由于患者依从性差和(或)合并其他代谢疾病,导致血糖控制效果不佳,在不用药物控制的前提下,真正能良好控制血糖的患者约占50%,故亟需一种额外治疗方式对其进行补充。随着内窥镜的发展,有人提出十二指肠黏膜表面重建术可以作为治疗2型糖尿病的辅助或替代方式,即通过内镜对十二指肠黏膜进行环形水热消融可以达到降低血糖和改善代谢的作用。本篇综述概述了十二指肠黏膜表面重建术的操作方式及其降糖机制。作为一种较新的技术,其安全性和疗效均需要在动物实验和临床研究中得到证据,旨在为更进一步的研究提供线索。
Abstract:
At present, most patients with type 2 diabetes mellitus are treated with a combination of diet, exercise and drugs. Patients with poor compliance and/or other metabolic diseases cannot control their blood sugar well. Only half of the patients can really control their blood glucose in normal. Therefore, an effective treatment to control the level of blood glucose is needed as supplement. With the development of endoscopy, it has been proposed that duodenal mucosal surface reconstruction can be used as an adjutant or alternative treatment method for type 2 diabetes mellitus. Duodenal mucosal surface reconstruction can reduce blood glucose and improve metabolism by endoscopic annular hydrothermal ablation of duodenal mucosa. In this review, we summarize the procedures and hypoglycemic mechanisms of duodenal mucosal surface reconstruction. Since it is a relatively new technique, it's safety and efficacy need to be demonstrated in animal and clinical studies aiming to provide clues for further research.

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备注/Memo

备注/Memo:
通信作者:张毅,Email:258521541@qq.com
更新日期/Last Update: 2022-04-20