参考文献/References:
[1] Norris SA,Osmond C,Gigante D,et al．Size at birth, weight gain in infancy and childhood, and adult diabetes risk in five low-or middle-income country birth cohorts[J]．Diabetes Care,2012,35（1）：72-79.
[2] Li Y,Qi Q,Workalemahu T,et al．Birth weight,genetic susceptibility,and adulthood risk of type 2 diabetes[J]．Diabetes Care,2012,35（12）：2479-2484.
[3] Dupuis J,Langenberg C,Prokopenko I,et al．New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk[J]．Nat Genet,2010,42（2）：105-116.
[4] Andersson EA,Harder MN,Pilgaard K,et al．The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associ-ates with elevated insulin release following an oral glucose challenge[J]．PLoS One,2011,6（11）：e27096.
[5] Freathy RM,Mook-Kanamori DO,Sovio U,et al．Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight[J]．Nat Genet,2010,42（5）：430-435.
[6] Horikoshi M,Yaghootkar H,Mook-Kanamori DO,et al．New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism[J]．Nat Genet,2013,45（1）：76-82.
[7] Vasan SK,Neville MJ,Antonisamy B,et al．Absence of birth-weight lowering effect of ADCY5 and near CCNL,but associa-tion of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians[J]．PLoS One,2011,6（6）：e21331.
[8] Andersson EA,Pilgaard K,Pisinger C,et al．Type 2 diabetes risk alleles near ADCY5,CDKAL1 and HHEX-IDE are associated with reduced birthweight[J]．Diabetologia,2010,53（9）：1908-1916.
[9] Mook-Kanamori DO,Marsh JA,Warrington NM,et al．Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth character-istics in different trimesters[J]．J Clin Endocrinol Metab,2011,96（5）：E810-E815.
[10] Ryckman KK,Feenstra B,Shaffer JR,et al．Replication of a genome-wide association study of birth weight in preterm neonates[J]．J Pediatr,2012,160（1）：19-24．e4.
[11] 陈莉明．糖尿病遗传学研究进展——2010年美国糖尿病协会年会侧记[J]．国际内分泌代谢杂志,2010,30（5）：299-301.
[12] Zhao J,Deliard S,Aziz A,et al．Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23[J]．BMC Med Genet,2012,13：89.
[13] Guo Q,Manolopoulou M,Bian Y,et al．Molecular basis for the recognition and cleavages of IGF-Ⅱ, TGF-alpha, and amylin by human insulin-degrading enzyme[J]．J Mol Biol,2010,395（2）：430-443.
[14] Okada Y,Kubo M,Ohmiya H,et al．Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations[J]．Nat Genet,2012,44（3）：302-306.
[15] Freathy RM,Bennett AJ,Ring SM,et al．Type 2 diabetes risk alleles are associated with reduced size at birth[J]．Diabetes,2009,58（6）：1428-1433.
[16] Pulizzi N,Lyssenko V,Jonsson A,et al．Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes[J]．Diabetologia,2009,52（5）：825-829.
[17] Zhao J,Li M,Bradfield JP,et al．Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene[J]．Diabetes,2009,58：2414-2418.
[18] Wu Y,Li H,Loos RJ,et al．Common variants in CDKAL1,CDKN2A/B,IGF2BP2,SLC30A8,and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population[J]．Diabetes,2008,57（10）：2834-2842.
[19] Winkler C,Illig T,Koczwara K,et al．HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes[J]．J Clin Endocrinol Metab,2009,94（10）：4113-4115.
[20] Bergvall N,Lindam A,Pawitan Y,et al．Importance of familial factors in associations between offspring birth weight and parental risk of type-2 diabetes[J]．Int J Epidemiol,2008,37（1）：185-192.
[21] Ng SF,Lin RC,Laybutt DR,et al．Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring[J]．Nature,2010,467（7318）：963-966.
[22] Ali Khan A,Rodriguez A,Sebert S,et al．The interplay of vari-ants near LEKR and CCNL1 and social stress in relation to birth size[J]．PLoS One,2012,7（6）：e38216.
[23] Freathy RM,Weedon MN,Bennett A,et al．Type 2 diabetes TCF7L2 risk genotypes alter birth weight：a study of 24,053 individuals[J]．Am J Hum Genet,2007,80（6）：1150-1161.
[24] Winkler C,Bonifacio E,Grallert H,et al．BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1[J]．Diabetes,2010,59（8）：2063-2067.
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