[1]田勍,肖文华,洪天配.应关注2型糖尿病患者的骨脆性变化[J].国际内分泌代谢杂志,2021,41(03):153-157.[doi:10.3760/cma.j.cn121383-20210301-03001]
 Tian Qing,Xiao Wenhua,Hong Tianpei..Attention is needed to bone fragility in patients with type 2 diabetes mellitus[J].International Journal of Endocrinology and Metabolism,2021,41(03):153-157.[doi:10.3760/cma.j.cn121383-20210301-03001]
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应关注2型糖尿病患者的骨脆性变化()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
41
期数:
2021年03期
页码:
153-157
栏目:
述评
出版日期:
2021-05-20

文章信息/Info

Title:
Attention is needed to bone fragility in patients with type 2 diabetes mellitus
作者:
田勍肖文华洪天配
北京大学第三医院内分泌科 100191
Author(s):
Tian Qing Xiao Wenhua Hong Tianpei.
Department of Endocrinology, Peking University Third Hospital, Beijing 100191, China
关键词:
2型糖尿病 降糖药物 骨脆性 骨折
Keywords:
Type 2 diabetes mellitus Antidiabetic medication Bone fragility Bone fracture
DOI:
10.3760/cma.j.cn121383-20210301-03001
摘要:
近年来,2型糖尿病(T2DM)患者的骨脆性变化日益受到重视。即使在骨密度正常时,T2DM患者的骨折风险仍可增加。T2DM患者骨脆性增加的影响因素众多,病理生理学机制较为复杂。此外,常用降糖药物对骨代谢的影响也各不相同。因此,关注T2DM患者的骨脆性变化,综合管理骨折风险,合理选择降糖药物治疗,是临床上必须引起重视的问题。
Abstract:
In recent years, the changes of bone fragility in patients with type 2 diabetes mellitus(T2DM)has attracted much attention. T2DM is associated with an increased risk of bone fracture even in the patients with normal bone mineral density. There are many factors contributing to the increased bone fragility in patients with T2DM, and its pathophysiological mechanisms are relatively complicated. Moreover, each antidiabetic medication also has different effect on bone metabolism. Therefore, attention should be paid to the changes of bone fragility, comprehensive management of fracture risk, and rational selection of antidiabetic drugs in patients with T2DM.

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备注/Memo

备注/Memo:
通信作者:洪天配,Email: tpho66@bjmu.edu.cn
更新日期/Last Update: 2021-05-20