[1]张如意 张桦 王娇 孙嘉 陈容平 杨锐 冉建民 陈宏.超重或肥胖2型糖尿病患者糖尿病足的 患病率及相关危险因素分析[J].国际内分泌代谢杂志,2015,(06):365-369.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.002]
　Zhang Ruyi*,Zhang Hua,Wang Jiao,et al.Prevalence and risk factors for diabetic foot in overweight or obese type 2 diabetic patients[J].International Journal of Endocrinology and Metabolism,2015,(06):365-369.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.002]
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超重或肥胖2型糖尿病患者糖尿病足的 患病率及相关危险因素分析()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年06期
页码:
365-369
栏目:
论著
出版日期:
2015-11-20

文章信息/Info

Title:
Prevalence and risk factors for diabetic foot in overweight or obese type 2 diabetic patients
作者:
张如意 张桦 王娇 孙嘉 陈容平 杨锐 冉建民 陈宏
510220 广州市红十字会医院内分泌科(张如意,冉建民); 450052 郑州大学第一附属医院内分泌与代谢病科(王娇); 510282 广州,南方医科大学珠江医院内分泌科(张桦,孙嘉,陈容平,杨锐,陈宏)
Author(s):
Zhang Ruyi*; Zhang Hua; Wang Jiao; Sun Jia; Chen Rongping; Yang Rui; Ran Jianmin; Chen Hong.
*Department of Endocrinology, Guangzhou Red Cross Hospital, Guangzhou 510220, China
关键词:
2型糖尿病;  超重;  肥胖;  糖尿病足;  患病率;  危险因素
Keywords:
Type 2 diabetes mellitus;  Overweight;  Obesity;  Diabetic foot;  Prevalence;  Risk factors
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.06.002
摘要:
目的 探讨糖尿病足在超重或肥胖2型糖尿病患者中的患病率,并分析其相关危险因素。方法 2011年8月至2012年3月,从广东省内60家医院纳入2型糖尿病且合并超重或肥胖的 4 037例患者作为研究对象,收集其病史、身高、体重、血糖、血脂、血肌酐、尿酸等资料,采用二分类Logistic回归分析该人群合并糖尿病足的相关危险因素。结果 本研究 4 037例超重或肥胖2型糖尿病患者中,208例合并糖尿病足,糖尿病足患病率为5.2%。二分类Logistic回归分析结果显示,年龄[优势比(OR)=1.018,95%CI:1.002～1.034)]、女性(OR=1.755,95%CI:1.118～2.755)、糖尿病病程(OR=1.038,95%CI:1.013～1.064)、体重指数(OR=1.226,95%CI:1.157～1.299)、HbA1c(OR=1.211,95%CI:1.135～1.293)、吸烟(OR=3.684,95%CI:2.339～5.803)、糖尿病肾病(OR=1.514,95%CI:1.013～2.263)和糖尿病周围神经病变(OR=2.250,95%CI:1.547～3.273)是糖尿病足的危险因素。结论 超重或肥胖的2型糖尿病患者糖尿病足患病率较高,对于该组人群,尤其是老年女性患者,应该及时平稳控制血糖,减轻体重,避免吸烟,注意定期筛查糖尿病肾病及周围神经病变等并发症。
Abstract:
Objective To investigate the prevalence and risk factors for diabetic foot in overweight or obese type 2 diabetic patients. Methods From August 2011 to March 2012, 4 037 subjects who were diagnosed as type 2 diabetes and with body mass index(BMI)≥24 kg/m2 were enrolled from 60 hospitals in Guangdong Province. History of disease, height, weight, the level of blood glucose, lipids, creatinine and uric acid were collected. Binary Logistic regression was used to analyze the risk factors for diabetic foot. Results There were 208 patients suffered from diabetic foot in 4 037 subjects who were diagnosed as type 2 diabetes and with BMI≥24 kg/m2. The prevalence of diabetic foot in this group was 5.2%. In the Binary Logistic regression analysis, presence of diabetic foot was positively associated with age[odd ratio(OR)=1.018,95%CI:1.002-1.034)], female(OR=1.755,95%CI:1.118-2.755), the duration of diabetes(OR=1.038,95%CI:1.013-1.064), BMI(OR=1.226,95%CI:1.157-1.299), HbA1c(OR=1.211,95%CI:1.135-1.293), smoking(OR=3.684,95%CI:2.339-5.803), diabetic nephropathy(OR=1.514,95%CI:1.013-2.263)and diabetic neuropathy(OR=2.250,95%CI:1.547-3.273). Conclusions The prevalence of diabetic foot is high in overweight or obese type 2 diabetic patients. For overweight or obese type 2 diabetic patients, especially the old female patients, controlling plasma glucose, decreasing body weight, quitting smoking and screening diabetes chronic complications such as diabetic nephropathy and diabetic neuropathy are important.

参考文献/References:

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备注/Memo

备注/Memo:
作者单位:510220 广州市红十字会医院内分泌科(张如意,冉建民); 450052 郑州大学第一附属医院内分泌与代谢病科(王娇); 510282 广州,南方医科大学珠江医院内分泌科(张桦,孙嘉,陈容平,杨锐,陈宏) 通信作者:陈宏,Email:rubychq@163.com
更新日期/Last Update: 2015-11-20