[1]刘宇翔,李代清.SGLT2抑制剂治疗2型糖尿病的临床研究[J].国际内分泌代谢杂志,2016,36(05):327-330.[doi:10.3760/cma.j.issn.1673-4157.2016.05.11]
 Liu Yuxiang,Li Daiqing.Clinical research of SGLT2 inhibitors for treating type 2 diabetes[J].International Journal of Endocrinology and Metabolism,2016,36(05):327-330.[doi:10.3760/cma.j.issn.1673-4157.2016.05.11]
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SGLT2抑制剂治疗2型糖尿病的临床研究()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
36
期数:
2016年05期
页码:
327-330
栏目:
综述
出版日期:
2016-09-20

文章信息/Info

Title:
Clinical research of SGLT2 inhibitors for treating type 2 diabetes
作者:
刘宇翔李代清
300070 天津医科大学内分泌研究所,卫生部激素与发育重点实验室
Author(s):
Liu Yuxiang Li Daiqing
Key Laboratory of Hormones and Development(Ministry of Health), The Institute of Endocrinology, Tianjin Medical University, Tianjin 300070, China
关键词:
2型糖尿病 SGLT2抑制剂 临床研究
Keywords:
Type 2 diabetes mellitus SGLT2 inhibitors Clinical treatment
DOI:
10.3760/cma.j.issn.1673-4157.2016.05.11
摘要:
钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂是一种治疗2型糖尿病的新型药物,其通过特异性地抑制肾 小管对葡萄糖的重吸收来降低血糖。目前,在欧美、日本等地已有大量的SGLT2抑制剂治疗2型糖尿病的临床试 验,这些临床研究表明,SGLT2抑制剂在降低糖化血红蛋白、空腹血糖、体重等方面表现出更好的效果以及更少 的不良反应。
Abstract:
Sodium-glucose co-transporters 2(SGLT2)inhibitors is a new drug used for the treatment of type 2 diabetes, which can directly decrease blood glucose concentration by blocking reabsorption of filtered glucose in the renal tubule. Nowadays, many clinical studies of SGLT2 inhibitors with the type 2 diabetes were developed in the US, Europe and Japan. These researches showed that SGLT2 inhibitors performed better in reducing HbA1c, fasting plasma glucose(FPG), body weight and had less side effects.

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备注/Memo

备注/Memo:
通信作者:李代清,Email:daiqingli68@163.com
更新日期/Last Update: 2016-11-20