参考文献/References:
[1] Tomaselli S, Panera N, Gallo A, et al. Circulating miRNA profiling to identify biomarkers of dysmetabolism[J].Biomark Med, 2012,6(6):729-742.
[2] Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis[J].Cardiovasc Res, 2008,79(4):581-588.
[3] Kumar M, Nath S, Prasad HK, et al. MicroRNAs: a new ray of hope for diabetes mellitus[J].Protein Cell, 2012,3(10):726-738
[4] Tattikota S G, Rathjen T, Mcanulty S J, et al. Argonaute2 mediates compensatory expansion of the pancreatic β cell[J].Cell Metab, 2014,19(1):122-134.
[5] Xia HQ, Pan Y, Peng J, et al. Over-expression of miR375 reduces glucose-induced insulin secretion in Nit-1 cells[J].Mol Biol Rep, 2011,38(5):3061-3065.
[6] Bala S, Marcos M, Szabo G. Emerging role of microRNAs in liver diseases[J].World J Gastroenterol, 2009,15(45):5633-5640.
[7] Szafranska AE, Davison TS, John J, et al. MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma[J].Oncogene, 2007,26(30):4442-4452.
[8] Dehwah MA, Xu A, Huang Q. MicroRNAs and type 2 diabetes/obesity[J].J Genet Genomics, 2012,39(1):11-18.
[9] Kong L, Zhu J, Han W, et al. Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study[J].Acta Diabetol, 2011,48(1):61-69.
[10] Clelland M, Kantharidis P. microRNA in the development of diabetic complications[J].Clin Sci(Lond), 2014,126(2):95-110.
[11] Tsukamoto Y, Nakada C, Noguchi T, et al. MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta[J].Cancer Res, 2010,70(6):2339-2349.
[12] Li Y, Jiang Q, Xia N, et al. Decreased expression of microRNA-375 in nonsmall cell lung Cancer and its clinical significance[J].J Int Med Res, 2012,40(5):1662-1669.
[13] Ling HY, Wen GB, Feng SD, et al. MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling[J].Clin Exp Pharmacol Physiol, 2011,38(4):239-246.
[14] Choi D, Woo M. Executioners of apoptosis in pancreatic {beta}-cells: not just for cell death[J].Am J Physiol Endocrinol Metab, 2010,298(4):E735-E741.
[15] Wei R, Yang J, Liu GQ, et al. Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells[J].Gene, 2013,518(2):246-255.
[16] Xu H, Tsang KS, Chan JC, et al. The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells[J].Cell Transplant, 2013,22(1):147-158.
[17] Koya V, Lu S, Sun YP, et al. Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy[J].Diabetes, 2008,57(3):757-769.
[18] Wang S, Jensen JN, Seymour PA, et al. Sustained neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function[J].Proc Natl Acad Sci U S A, 2009,106(24):9715-9720.
[19] Schaffer AE, Taylor BL, Benthuysen JR, et al. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity[J].PLoS Genet, 2013,9(1):e1003274.
[20] Liu SH, Rao DD, Nemunaitis J, et al. PDX-1 is a therapeutic target for pancreatic Cancer, insulinoma and islet neoplasia using a novel RNA interference platform[J].PLoS One, 2012,7(8):e40452.
[21] Poy MN,Hausser J,Trajkovski M, et al. miR-375 maintains nor-mal pancreatic alphand beta-cell mass[J].Proc Natl Acad Sci U S A, 2009,106(14):5813-5818.
[22] Kinoshita T, Nohata N, Yoshino H, et al. Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma[J].Int J Oncol, 2012,40(1):185-193.
[23] Vickers K C, Palmisano B T, Shoucri B M, et al. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins[J].Nat Cell Biol, 2011,13(4):423-433.
[24] El Ouaamari A, Baroukh N, Martens GA, et al. miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells[J].Diabetes, 2008,57(10):2708-2717.
[25] Arikoglu H, Ozdemir H, Kaya DE, et al. The adiponectin variants contribute to the genetic background of type 2 diabetes in Turkish population[J].Gene, 2014,534(1):10-16.
[26] Zampetaki A, Mayr M. MicroRNAs in vascular and metabolic disease[J].Circ Res, 2012,110(3):508-522.
[27] Li Y, Xu X, Liang Y, et al. miR-375 enhances palmitate-induced lipoapoptosis in insulin-secreting NIT-1 cells by repressing myotrophin(V1)protein expression[J].Int J Clin Exp Pathol, 2010,3(3):254-264.
[28] Wang Y, Huang C, Reddy Chintagari N, et al. miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/β-catenin pathway[J].Nucleic Acids Res, 2013,41(6):3833-3844.
[29] Qin L, Chen Y, Niu Y, et al. A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway[J].BMC Genomics,2010,11:320.
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