[1]马豆豆,李宁,范志宏.Chemerin研究进展[J].国际内分泌代谢杂志,2014,(05):310-312.[doi:10.3760/cma.j.issn.1673-4157.2014.05.006]
 Ma Doudou,Li Ning,Fan Zhihong..The progress of chemerin research[J].International Journal of Endocrinology and Metabolism,2014,(05):310-312.[doi:10.3760/cma.j.issn.1673-4157.2014.05.006]
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Chemerin研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年05期
页码:
310-312
栏目:
综述
出版日期:
2014-10-31

文章信息/Info

Title:
The progress of chemerin research
作者:
马豆豆李宁范志宏
030001 太原, 山西医科大学第二医院内分泌科
Author(s):
Ma DoudouLi NingFan Zhihong.
Department of Endocrinology,The Second Hospital of Shanxi Medical University,Taiyuan 030001,China Corresponding author:Fan Zhihong,Email:fanzhih618@163.com
关键词:
Chemerin 炎症 葡萄糖稳态
Keywords:
Chemerin Inflammation Glucose homeostasis
DOI:
10.3760/cma.j.issn.1673-4157.2014.05.006
摘要:
Chemerin是一种免疫调节因子,在炎性反应相关的一系列蛋白酶作用下可对白细胞产生趋化作用,并参与炎性反应。同时chemerin也是一种调节脂肪细胞生成、代谢及葡萄糖稳态的脂肪因子,其参与了肥胖及代谢综合征的发生、发展。近年来研究发现chemerin对糖尿病及代谢综合征具有一定的诊断意义,且其有可能成为治疗相关疾病的新靶点。
Abstract:
Chemerin is an immunomodulating factor which is processed by a variety of proteases linked to inflammation to induce chemotaxis in leukocyte. Meanwhile, chemerin is a novel adipokine that regulates adipocyte development and metabolic function as well as glucose homeostasis, and takes part in the occurrence and development of obesity and metabolic syndrome.Recent years, studies show that chemerin may be helpful for diagnosis of diabetes and metabolic syndrome,and it may become a new target for the treatment of related disorders.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:山西省科技攻关项目(20130313017-9) 通信作者:范志宏,Email:fanzhih618@163.com
更新日期/Last Update: 2014-09-20