[1]沙宇菁,李彦彦,杨玲.白脂素与2型糖尿病及其血管并发症的研究进展[J].国际内分泌代谢杂志,2021,41(02):133-137.[doi:10.3760/cma.j.cn121383-20200603-06007]
　Sha Yujing,Li Yanyan,Yang Ling.Research progress of asprosin in type 2 diabetes mellitus and its vascular complications[J].International Journal of Endocrinology and Metabolism,2021,41(02):133-137.[doi:10.3760/cma.j.cn121383-20200603-06007]
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白脂素与2型糖尿病及其血管并发症的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
41
期数:
2021年02期
页码:
133-137
栏目:
综述
出版日期:
2021-03-20

文章信息/Info

Title:
Research progress of asprosin in type 2 diabetes mellitus and its vascular complications
作者:
沙宇菁; 李彦彦; 杨玲
江苏大学附属医院内分泌代谢科,镇江 212000
Author(s):
Sha Yujing;  Li Yanyan;  Yang Ling
Department of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang 212000, China
关键词:
白脂素;  2型糖尿病;  糖尿病大血管并发症;  糖尿病微血管并发症
Keywords:
Asprosin;  Type 2 diabetes;  Diabetic macrovascular diseases;  Diabetic microvascular diseases
DOI:
10.3760/cma.j.cn121383-20200603-06007
摘要:
白脂素(asprosin)是一种新型葡萄糖调控蛋白激素,其主要由白色脂肪细胞合成分泌。Asprosin可通过增强胰岛素抵抗、调节胰岛素分泌、影响食欲参与糖脂代谢,从而调节血糖稳态。此外,研究发现Asprosin与糖尿病大血管并发症及糖尿病微血管并发症存在较多联系,但具体机制尚不清楚。深入探讨Asprosin与糖尿病及其血管并发症的作用机制,可为糖尿病及其血管并发症的治疗提供新靶点。
Abstract:
Asprosin is a new type of glucose regulatory protein hormone, which is mainly synthesized and secreted by white adipocytes. Asprosin can regulate glucose homeostasis by enhancing insulin resistance, regulating insulin secretion and affecting appetite. In addition, studies have found that asprosin is associated with diabetic macrovascular complications and diabetic microvascular complications, but the specific mechanism is not clear. In order to provide a new target for the treatment of diabetes mellitus and its vascular complications, the mechanism of asprosin in diabetes mellitus and its vascular complications should be explored.

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备注/Memo

备注/Memo:
通信作者:杨玲,Email:1027322959@qq.com 基金项目:江苏省预防医学科研课题(Y2018109)
更新日期/Last Update: 2021-03-20