[1]冯娟,夏维波.维生素D结合蛋白研究进展[J].国际内分泌代谢杂志,2016,36(03):209-213.[doi:10.3760/cma.j.issn.1673-4157.2016.03.17]
 Feng Juan,Xia Weibo.Research progress of vitamin D binding protein[J].International Journal of Endocrinology and Metabolism,2016,36(03):209-213.[doi:10.3760/cma.j.issn.1673-4157.2016.03.17]
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维生素D结合蛋白研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
36
期数:
2016年03期
页码:
209-213
栏目:
综述
出版日期:
2016-05-20

文章信息/Info

Title:
Research progress of vitamin D binding protein
作者:
冯娟夏维波
100730 中国医学科学院北京协和医学院,北京协和医院内分泌科,卫生部内分泌重点实验室
Author(s):
Feng JuanXia Weibo
Key Laboratory of Endocrinology of The Ministry of Health,Department of Endocrinology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
关键词:
维生素D结合蛋白 基因多态性 维生素D 骨质疏松
Keywords:
Vitamin D binding protein Gene Polymorphism Vitamin D Osteoporosis
DOI:
10.3760/cma.j.issn.1673-4157.2016.03.17
摘要:
维生素D结合蛋白(DBP)最初被称为簇特异性成分(group-specific component),简称Gc蛋白,是一种多功能的糖蛋白,具有高度多态性,DBP基因多态性会影响其水平及其与维生素D及其代谢产物的亲和力,从而可能影响功能性25(OH)D3水平。它不仅与骨质疏松相关,同时也与多种骨外疾病相关。
Abstract:
Vitamin D binding protein(DBP), originally known as group-specific component(Gc-globulin), is a multifunctional glycoprotein with high polymorphism.In addition,the polymorphism may influence the level of DBP and its affinity with vitamin D and its metabolites,which may eventually influence the level of functional 25-hydroxyvitamin D3.DBP not only has an association with osteoporosis, but also with a variety of diseases outside bone.

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更新日期/Last Update: 2016-05-20