[1]贺文娟 钟燕.肠道菌群及其代谢产物与肥胖的关系[J].国际内分泌代谢杂志,2018,38(01):40-43.[doi:10.3760/cma.j.issn.1673-4157.2018.01.011]
 He Wenjuan,Zhong Yan..Relationship between gut microbiota,its metabolites and obesity[J].International Journal of Endocrinology and Metabolism,2018,38(01):40-43.[doi:10.3760/cma.j.issn.1673-4157.2018.01.011]
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肠道菌群及其代谢产物与肥胖的关系()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年01期
页码:
40-43
栏目:
综述
出版日期:
2018-01-20

文章信息/Info

Title:
Relationship between gut microbiota,its metabolites and obesity
作者:
贺文娟 钟燕
410007 长沙,南华大学儿科学院,湖南省儿童医院儿童保健所
Author(s):
He Wenjuan Zhong Yan.
Children's Healthcare Institution,Hunan Children Hosptial,The University of South China Academy of Pediatrics,Changsha 410007,China
关键词:
肠道菌群 肥胖 代谢产物 短链脂肪酸 脂多糖 甲烷
Keywords:
Gut microbiota Obesity Metabolites Short-chain fatty acids Lipopolysaccharide Methane
DOI:
10.3760/cma.j.issn.1673-4157.2018.01.011
摘要:
研究发现,肠道菌群参与肥胖的发病过程,且作为肠道菌群的重要代谢产物:短链脂肪酸、脂多糖、甲烷、氧化三甲胺等,通过提高对能量物质的获取,引起机体的慢性炎性反应,减慢肠道蠕动以提高吸收效率,造成胆固醇在细胞内的堆积,从而诱导肥胖、胰岛素抵抗,促进动脉粥样硬化斑块的形成。
Abstract:
Studies have found that gut microbiota played an indispensable role in the pathogenesis of obesity. And as important metabolites of gut microbiota: short chain fatty acids, lipopolysaccharides, methane, trimethylamine etc, can increase the acquisition of energy material, cause chronic inflammation of the body, slow the intestinal peristalsis to promote the absorption efficiency, result in the accumulation of cholesterol in the cells, thereby induce obesity, insulin resistance, and promote the accumulation of atherosclerotic plaques formation.

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备注/Memo

备注/Memo:

通信作者:钟燕,Email:zhongyan@163.com
更新日期/Last Update: 2018-01-30