[1]刘剑 吴明昊 高宇.高脂饮食影响消化系统致肥胖的机制[J].国际内分泌代谢杂志,2015,(06):402-405.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.011]
　Liu Jian*,Wu Minghao,Gao Yu..The mechanism of obesity caused by disturbance of high fat diets on gastrointestinal system[J].International Journal of Endocrinology and Metabolism,2015,(06):402-405.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.011]
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高脂饮食影响消化系统致肥胖的机制()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年06期
页码:
402-405
栏目:
基础研究
出版日期:
2015-11-20

文章信息/Info

Title:
The mechanism of obesity caused by disturbance of high fat diets on gastrointestinal system
作者:
刘剑 吴明昊 高宇
067000 承德医学院研究生学院(刘剑,吴明昊); 067000 承德医学院附属医院内分泌科(高宇)
Author(s):
Liu Jian*; Wu Minghao;  Gao Yu.
*Graduate School of Chengde Medical College, Chengde 067000,China
关键词:
高脂饮食;  肥胖;  脂质感应;  胃肠道激素;  微生物群
Keywords:
High-fat diet;  Obesity;  Lipid detection;  Gut peptides;  Microbiota
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.06.011
摘要:
肥胖是指体内脂肪堆积过多和(或)分布异常的一种慢性代谢性疾病。肥胖的病因未明,目前认为与遗传因素、环境因素等多种因素相互作用有关。高脂饮食是与肥胖存在紧密联系的环境因素之一,但相关作用机制仍不明确,可能与长期高脂饮食所致的消化道脂质感应信号通路受损、胃肠道激素分泌紊乱、肠道菌群的改变有关。
Abstract:
Obesity is a chronic metabolic disease,which refers to the abnormal fat distribution and(or)excessive fat accumulation. The cause of obesity is unknown, but is associated with various factors including genetic factors and environmental factors. There is a strong direct association between high-fat diet and obesity. However, the mechanisms of chronic high-fat consumption in the development of obesity are still poorly understood. Accumulating evidence shows that the mechanisms may be related to gastrointestinal lipid detection,abnormal secretion of gut peptides, and change of intestinal microbiota.

参考文献/References:

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备注/Memo

备注/Memo:
作者单位:067000 承德医学院研究生学院(刘剑,吴明昊); 067000 承德医学院附属医院内分泌科(高宇) 通信作者:高宇,Email:yugao815@163.com
更新日期/Last Update: 2015-11-20