参考文献/References:
[1] Yates LA,Norbury CJ,Gilbert RJ.The long and short of microRNA[J].Cell,2013,153（3）：516-519.
[2] Kadowaki T,Ueki K,Yamauchi T,et al.SnapShot：Insulin signaling pathways[J]. Cell,2012,148（3）,624,624.e1.
[3] He A,Zhu L,Gupta N,et al.Overexpression of micro ribonucleic acid 29,highly up-regulated in diabetic rats,leads to insulin resistance in 3T3-L1 adipocytes[J].Mol Endocrinol,2007,21（11）,
2785-2794.
[4] Dávalos A,Goedeke L,Smibert P,et al.miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling[J].Proc Natl Acad Sci U S A,2011,108（22）,9232-9237.
[5] Ryu HS,Park SY,Ma D,et al.The induction of microRNA targeting IRS-1 is involved in the development of insulin resis-tance under conditions of mitochondrial dysfunction in hepato-cytes[J].PLoS One,2011,6（3）：e17343.
[6] Jordan SD,Krüger M,Willmes DM,et al.Obesity-induced over-expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism[J].Nat Cell Biol,2011,13（4）：434-446.
[7] Trajkovski M,Hausser J,Soutschek J,et al.MicroRNAs 103 and 107 regulate insulin sensitivity[J].Nature,2011,474（7353）：649-653.
[8] Kornfeld JW,Baitzel C,K?觟nner AC,et al.Obesity-induced over-expression of miR-802 impairs glucose metabolism through silencing of Hnf1b[J].Nature,2013,494（7435）：111-115.
[9] Wen F,Yang Y,Jin D,et al.MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells[J]. Biochem Biophys Res Commun,2014,445（2）：517-523.
[10] Zhou B,Li C, Qi W,et al.Downregulation of miR-181a upregu-lates sirtuin-1 （SIRT1） and improves hepatic insulin sensitivity[J].Diabetologia,2012,55（7）：2032-2043.
[11] Yang YM,Seo SY,Kim TH,et al.Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B,which is reversed by licorice flavonoid[J].Hepatology,2012,56(6)：2209-2220.
[12] Kl?觟ting N,Berthold S,Kovacs P,et al.MicroRNA expression in human omental and subcutaneous adipose tissue[J].PLoS One,2009,4（3）：e4699.
[13] Civelek M,Hagopian R,Pan C,et al.Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits[J].Hum Mol Genet,2013,22（15）：3023-3037.
[14] Arner E,Mejhert N,Kulyté A,et al.Adipose tissue microRNAs as regulators of CCL2 production in human obesity[J].Diabetes,2012,61（8）：1986-1993.
[15] Huang B,Qin W,Zhao B,et al.MicroRNA expression profiling in diabetic GK rat model[J].Acta Biochim Biophys Sin（Shang-hai）,2009,41（6）：472-477.
[16] Granjon A,Gustin MP,Rieusset J.et al.The microRNA signature in response to insulin reveals its implication in the transcriptional action of insulin in human skeletal muscle and the role of a sterol regulatory element-binding protein-1c/myocyte enhancer factor 2C pathway[J].Diabetes,2009,58（11）：2555-2564 .
[17] Zhu H,Shyh-Chang N,Segrè AV,et al.The Lin28/let-7 axis regulates glucose metabolism[J].Cell,2011,147（1）：81-94.
[18] Frost RJ,Olson EN.Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs[J].Proc Natl Acad Sci USA,2011,108（52）：21075-21080.
[19] Lee H,Jee Y,Hong K,et al.MicroRNA-494,upregulated by tumor necrosis factor-alpha,desensitizes insulin effect in C2C12 muscle cells[J].PLoS One,2013,8（12）：e83471.
[20] Chen GQ,Lian WJ,Wang GM,et al.Altered microRNA expres-sion in skeletal muscle results from high-fat diet-induced insulin resistance in mice[J].Mol Med Rep,2012,5（5）：1362-1368.
[21] Zhang Y,Yang L,Gao YF,et al.MicroRNA-106b induces mito-chondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2[J].Mol Cell Endocrinol,2013,381（1-2）：230-240.
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