[1]梁杏燕,赵捷,马红霞.自身免疫性甲状腺疾病对多囊卵巢综合征不良妊娠结局的影响[J].国际内分泌代谢杂志,2022,42(06):481-484.[doi:10.3760/cma.j.cn121383-20211016-10036]
 Liang Xingyan,Zhao Jie,Ma Hongxia..Influence of autoimmune thyroid disease on adverse pregnant outcome in polycystic ovary syndrome[J].International Journal of Endocrinology and Metabolism,2022,42(06):481-484.[doi:10.3760/cma.j.cn121383-20211016-10036]
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自身免疫性甲状腺疾病对多囊卵巢综合征不良妊娠结局的影响()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年06期
页码:
481-484
栏目:
综述
出版日期:
2022-11-20

文章信息/Info

Title:
Influence of autoimmune thyroid disease on adverse pregnant outcome in polycystic ovary syndrome
作者:
梁杏燕1赵捷2马红霞1
1广州医科大学附属第一医院中西医结合妇科 510000; 2北京大学第三医院生殖医学中心 100000
Author(s):
Liang Xingyan1 Zhao Jie2 Ma Hongxia1.
1Department of Integrated Traditional Chinese and Western Medicine Gynecology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510000, China; 2Center of Reproductive Medicine, Peking University Third Hospital, Beijing 100000, China
关键词:
多囊卵巢综合征 自身免疫性甲状腺疾病 妊娠结局 胰岛素抵抗 炎症
Keywords:
Polycystic ovary syndrome Autoimmune thyroid disease Pregnancy outcome Insulin resistance Inflammation
DOI:
10.3760/cma.j.cn121383-20211016-10036
摘要:
多囊卵巢综合征(PCOS)和自身免疫性甲状腺疾病(AITD)是育龄女性常见的内分泌代谢性疾病和慢性炎性疾病,妊娠女性因患病发生自然流产、妊娠期糖尿病和早产等不良妊娠结局的风险明显增高。PCOS患者更易合并AITD,甲状腺功能异常会进一步加重PCOS患者的症状及带来一定的生育问题。目前发生机制仍不明确,但认为AITD对PCOS患者在胰岛素抵抗、糖脂代谢、性激素紊乱、维生素D代谢异常等病理状态中存在一定影响。因此,分析AITD对PCOS患者病理状态的影响及机制,对预防妊娠并发症的发生及改善妊娠结局有重要意义。
Abstract:
Polycystic ovary syndrome(PCOS)and autoimmune thyroid disease(AITD)are endocrine and metabolic diseases and chronic inflammatory diseases common in women of reproductive age, which significantly increase the risk of adverse pregnancy outcomes, such as spontaneous abortion, gestational diabetes and premature delivery. The women with PCOS are prone to have AITD, and abnormal thyroid function can further aggravate the performance and reproductive problems in patients with PCOS. Although the pathogenesis of PCOS and AITD are still unclear currently, it is considered that AITD has an influence on pathological conditions such as insulin resistance, abnormal glucose and lipid metabolism, sex hormone disorders, unhealthy vitamin D status in patients with PCOS. Therefore, it is of great significance to analyze and elaborate the effect and mechanism of AITD on the pathological status of PCOS patients for preventing the occurrence of complications and improving pregnancy outcomes in patients with PCOS.

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备注/Memo

备注/Memo:
通信作者:马红霞,Email:doctorhongxia@126.com
更新日期/Last Update: 2022-12-01