[1]赫晓晴 单忠艳.肠道菌群与自身免疫性甲状腺疾病[J].国际内分泌代谢杂志,2020,40(03):179-183.[doi:10.3760/cma.j.issn.1673-4157.2020.03.008]
 He Xiaoqing,Shan Zhongyan.Gut microbiota and autoimmune thyroid disease[J].International Journal of Endocrinology and Metabolism,2020,40(03):179-183.[doi:10.3760/cma.j.issn.1673-4157.2020.03.008]
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肠道菌群与自身免疫性甲状腺疾病()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
40
期数:
2020年03期
页码:
179-183
栏目:
综述
出版日期:
2020-05-20

文章信息/Info

Title:
Gut microbiota and autoimmune thyroid disease
作者:
赫晓晴 单忠艳
中国医科大学附属第一医院内分泌与代谢病科,沈阳 110001
Author(s):
He Xiaoqing Shan Zhongyan
Department of Endocrinology and Metabolism, The First Affiliated Hospital of China Medical University, Shenyang 110001, China
关键词:
肠道菌群 Graves病 自身免疫性甲状腺炎
Keywords:
Intestinal flora Graves' disease Autoimmune thyroiditis
DOI:
10.3760/cma.j.issn.1673-4157.2020.03.008
摘要:
肠道菌群不仅维持消化系统平衡,对免疫、激素和代谢稳态也至关重要。自身免疫性甲状腺疾病(AITD)是内分泌系统最常见的自身免疫性疾病,由桥本甲状腺炎和Graves病等一系列疾病组成。近期研究发现,AITD患者肠道菌群与健康人群相比存在差异。肠道菌群可能通过影响甲状腺激素的代谢及激发机体交叉免疫反应,参与AITD的发生、发展。
Abstract:
Intestinal flora not only maintains the balance of the digestive system, but also is important for immune, hormones and metabolic homeostasis. Autoimmune thyroid disease(AITD)is the most common autoimmune disease in the endocrine system. It consists of a series of diseases such as Hashimoto's thyroiditis and Graves's disease. Recent studies have found that the intestinal flora between patients with AITD and healthy people is different. The intestinal flora may participate in the pathogenesis of AITD by affecting the the metabolism of thyroid hormones and stimulating cross immunity.

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备注/Memo

备注/Memo:
通信作者:单忠艳,Email:cmushanzhongyan@163.com
基金项目:国家自然科学基金(U1508219)
Corresponding author: Shan Zhongyan, Email:cmushanzhongyan@163.com
Fund program:National Natural Science Foundation of China(U1508219)
更新日期/Last Update: 2020-05-20