[1]刁世童 陈宏 阮玉婷.长链非编码RNA与糖代谢调节[J].国际内分泌代谢杂志,2018,38(03):196-199.[doi:10.3760/cma.j.issn.1673-4157.2018.03.013]
 Diao Shitong*,Chen Hong,Ruan Yuting.*.Long non-coding RNA associated with glycometabolism regulation[J].International Journal of Endocrinology and Metabolism,2018,38(03):196-199.[doi:10.3760/cma.j.issn.1673-4157.2018.03.013]
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长链非编码RNA与糖代谢调节()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年03期
页码:
196-199
栏目:
基础研究
出版日期:
2018-05-20

文章信息/Info

Title:
Long non-coding RNA associated with glycometabolism regulation
作者:
刁世童 陈宏 阮玉婷
510515 广州,南方医科大学第二临床医学院(刁世童); 510282 广州,南方医科大学珠江医院内分泌代谢科(陈宏、阮玉婷) 通信作者:阮玉婷,Email:dr_tracy@126.com
Author(s):
Diao Shitong* Chen Hong Ruan Yuting.*
Second College of Clinical Medicine, Southern Medical University, Guangzhou 510515, China
关键词:
长链非编码RNA 葡萄糖稳态 糖尿病
Keywords:
Long non-coding RNA Glucose homeostasis Diabetes mellitus
DOI:
10.3760/cma.j.issn.1673-4157.2018.03.013
摘要:
长链非编码RNA(lncRNA)是一类转录长度大于200个核苷酸单位的非编码RNA,在转录沉默、转录激活、染色体修饰、核内运输等方面起重要作用。LncRNA调节多种生物学功能,与人类多种疾病的发生、发展密切相关。糖代谢是人体基本的生化过程之一,lncRNA可通过调控胰腺、肝脏、脂肪和骨骼肌的糖代谢参与糖尿病进程。
Abstract:
Long non-coding RNA(lncRNA)is a kind of non-coding RNA that transcribes more than 200 nucleotide units. It plays an important role in transcription silence, transcription activation, chromosomal modification and intranuclear transportation. LncRNA regulates many biological function and is closely correlated with the occurance and development of human diseases. Glucose metabolism is one of the basic biochemical processes in human body. LncRNA can participate in the processes of diabetes through the regulation of glucose metabolism in pancreas, liver, fat and skeletal muscle.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81570716); 广东省自然科学基金(2016A030313633); 南方医科大学2017年国家级大学生创新训练计划项目(201712121046)
更新日期/Last Update: 2018-03-30