[1]杨晶晶,徐书杭,刘超.甲状腺滤泡性肿瘤术前诊断及诊断模型研究进展[J].国际内分泌代谢杂志,2023,43(01):34-37.[doi:10.3760/cma.j.cn121383-20210816-08042]
　Yang Jingjing,Xu Shuhang,Liu Chao..Update on preoperative diagnosis and diagnostic model of thyroid follicular neoplasm[J].International Journal of Endocrinology and Metabolism,2023,43(01):34-37.[doi:10.3760/cma.j.cn121383-20210816-08042]
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甲状腺滤泡性肿瘤术前诊断及诊断模型研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
43
期数:
2023年01期
页码:
34-37
栏目:
综述
出版日期:
2023-01-20

文章信息/Info

Title:
Update on preoperative diagnosis and diagnostic model of thyroid follicular neoplasm
作者:
杨晶晶1; 2; 徐书杭1; 刘超1
1南京中医药大学附属中西医结合医院内分泌科,南京 210028; 2南京中医药大学,南京 210023
Author(s):
Yang Jingjing1; 2;  Xu Shuhang1;  Liu Chao1.
1Department of Endocrinology and Metabolism, Affiliated Hospital of Integration of Chinese and Western Medicine in Jiangsu Province, Nanjing 210028, China; 2Nanjing University of Traditional Chinese Medicine, Nanjing 210023, China
关键词:
滤泡性肿瘤;  甲状腺滤泡性腺瘤;  甲状腺滤泡状癌;  诊断预测模型
Keywords:
Follicular neoplasm;  Follicular adenoma;  Follicular thyroid carcinoma;  Diagnostic model
DOI:
10.3760/cma.j.cn121383-20210816-08042
摘要:
甲状腺滤泡性肿瘤是一类缺乏甲状腺乳头状癌核特征的滤泡上皮起源肿瘤,主要包括甲状腺滤泡性腺瘤和甲状腺滤泡状癌。甲状腺滤泡性肿瘤的术前诊断具有一定挑战性。超声、细胞学检查、分子检测等单一地用于评估甲状腺结节良恶性的检查方法,难以将甲状滤泡状癌与其他滤泡性病变区分出来。包括临床特征在内的多因素风险评估诊断预测模型可能有助于甲状腺滤泡状癌的术前鉴别诊断。
Abstract:
Follicular neoplasm is a type of follicular epithelial-derived tumor lacking the nuclear features of papillary thyroid carcinoma, including thyroid follicular adenoma and thyroid follicular carcinoma. Preoperative diagnosis of thyroid follicular neoplasms is still challenging. Single method like thyroid ultrasound, cytology, molecular test, is not sufficient to distinguish thyroid follicular carcinoma from other follicular lesions. Diagnostic models that include clinical features and multifactorial risk scores may contribute to the preoperatively differential diagnosis of thyroid follicular carcinoma.

参考文献/References:

[1] Dralle H,Machens A,Basa J,et al.Follicular cell-derived thyroid cancer[J].Nat Rev Dis Primers,2015,1:15077.DOI:10.1038/nrdp.2015.77.
[2] Grani G,Lamartina L,Durante C,et al.Follicular thyroid cancer and Hürthle cell carcinoma: challenges in diagnosis, treatment, and clinical management[J].Lancet Diabetes Endocrinol,2018,6(6):500-514.DOI:10.1016/S2213-8587(17)30325-X.
[3] Kuo TC,Wu MH,Chen KY,et al.Ultrasonographic features for differentiating follicular thyroid carcinoma and follicular adenoma[J].Asian J Surg,2020,43(1):339-346.DOI:10.1016/j.asjsur.2019.04.016.
[4] Russ G,Bonnema SJ,Erdogan MF,et al.European Thyroid Association Guidelines for ultrasound malignancy risk stratification of thyroid nodules in adults:The EU-TIRADS[J].Eur Thyroid J,2017,6(5):225-237.DOI:10.1159/000478927.
[5] Li W,Song Q,Lan Y,et al.The value of sonography in distinguishing follicular thyroid carcinoma from adenoma[J].Cancer Manag Res,2021,13:3991-4002.DOI:10.2147/CMAR.S307166.
[6] Cibas ES,Ali SZ.The 2017 Bethesda ystem for reporting thyroid cytopathology[J].Thyroid,2017,27(11):1341-1346.DOI:10.1089/thy.2017.0500.
[7] VandenBussche CJ,Olson MT,Adams C,et al.Cytotechnologist performance for screening microfollicular atypia in indeterminate thyroid fine-needle aspirates[J].Acta Cytol,2014,58(5):432-438.DOI:10.1159/000367882.
[8] Na HY,Moon JH,Choi JY,et al.Preoperative diagnostic categories of fine needle aspiration cytology for histologically proven thyroid follicular adenoma and carcinoma,and Hurthle cell adenoma and carcinoma:analysis of cause of under-or misdiagnoses[J].PLoS One,2020,15(11):e024159.DOI:10.1371/journal.pone.0241597.
[9] Yoon RG,Baek JH,Lee JH,et al.Diagnosis of thyroid follicular neoplasm:fine-needle aspiration versus core-needle biopsy[J].Thyroid,2014,24(11):1612-1617.DOI:10.1089/thy.2014.0140.
[10] Bai Y,Kakudo K,Jung CK.Updates in the pathologic classification of thyroid neoplasms:a review of the World Health Organization classification[J].Endocrinol Metab(Seoul),2020,35(4):696-715.DOI:10.3803/EnM.2020.807.
[11] Yim Y,Baek JH.Core needle biopsy in the management of thyroid nodules with an indeterminate fine-needle aspiration report[J].Gland Surg,2019,8(Suppl 2):S77-S85.DOI:10.21037/gs.2018.09.07.
[12] Haugen BR,Alexander EK,Bible KC,et al.2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer:the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer[J].Thyroid,2016,26(1):1-133.DOI:10.1089/thy.2015.0020.
[13] 刘志艳.分化性甲状腺癌形态学谱系与分子生物学特征[J].中华病理学杂志,2020,49(3):284-288.DOI:10.3760/cma.j.issn.0529-5807.2020.03.018.
[14] Acquaviva G,Visani M,Repaci A,et al.Molecular pathology of thyroid tumours of follicular cells:a review of genetic alterations and their clinicopathological relevance[J].Histopathology,2018,72(1):6-31.DOI: 10.1111/his.13380.
[15] Borowczyk M,Szczepanek-Parulska E,Dbicki S,et al.Differences in mutational profile between follicular thyroid carcinoma and follicular thyroid adenoma identified using next generation sequencing[J].Int J Mol Sci,2019,20(13):3126.DOI:10.3390/ijms20133126.
[16] Xu PP,Zeng S,Xia XT, et al. FAM172A promotes follicular thyroid carcinogenesis and may be a marker of FTC[J].Endocr Relat Cancer,2020,27(11): 657-669.DOI:10.1530/ERC-20-0181.
[17] Englum BR,Pura J,Reed SD,et al.A bedside risk calculator to preoperatively distinguish follicular thyroid carcinoma from follicular variant of papillary thyroid carcinoma[J].World J Surg,2015,39(12):2928-2934.DOI:10.1007/s00268-015-3192-4.
[18] Yu Q,Liu K,Xie C,et al.Development and validation of a preoperative prediction model for follicular thyroid carcinoma[J].Clin Endocrinol(Oxf), 2019,91(2):348-355.DOI:10.1111/cen.14002.
[19] Slutzky-Shraga I,Sternov Y,Robenshtock E,et al.Be aware of the patient with benign follicular thyroid lesion histology and rising thyroglobulin level[J].Endocr Pract,2018,24(8):740-745.DOI:10.4158/EP-2018-0052.
[20] Ianni F,Pascucci D,Paragliola RM,et al.Follow-up or surgery for indeterminate thyroid nodules:could the CUT score application be a support for decision-making in the preoperative assessment[J].Thyroid,2020,30(1):65-71.DOI:10.1089/thy.2018.0649.
[21] Ustun B,Chhieng D,Prasad ML,et al.Follicular variant of papillary thyroid carcinoma: accuracy of FNA diagnosis and implications for patient management[J].Endocr Pathol,2014,25(3):257-264.DOI:10.1007/s12022-014-9301-3.

备注/Memo

备注/Memo:
通信作者:徐书杭,Email: shuhangxu@163.com
基金项目:江苏省重点研发计划项目(BE2020726); 江苏省卫生健康委医学科研项目(M2020102)
更新日期/Last Update: 2023-01-30