参考文献/References:
[1] Ogurtsova K, da Rocha Fernandes JD, Huang Y, et al. IDF diabetes atlas:global estimates for the prevalence of diabetes for 2015 and 2040[J]. Diabetes Res Clin Pract, 2017,128(40-50):123-126.DOI:10.1016/j.diabres.2017.03.024.
[2] Meier JJ, Bhushan A, Butler AE, et al. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes:indirect evidence for islet regeneration?[J]. Diabetologia,2005,48(11):2221-2228.DOI:10.1007/s00125-005-1949-2.
[3] Butler AE, Janson J, Bonner-Weir S,et al. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes[J]. Diabetes,2003,52(1):102-110.DOI: 10.2337/diabetes.52.1.102.
[4] Morán I, Akerman I, van de Bunt M, et al. Human beta cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes [J]. Cell Metab,2012,16(4):435-448.DOI:10.1016/j.cmet.2012.08.010.
[5] Ku GM, Kim H, Vaughn IW, et al. Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome [J]. Mol Endocrinol,2012,26(10):1783-1792.DOI:10.1210/me.2012-1176.
[6] Bramswig NC, Everett LJ, Schug J, et al. Epigenomic plasticity enables human pancreatic α to β cell reprogramming [J]. J Clin Invest,2013,123(3):1275-1284.DOI:10.1172/JCI66514.
[7] Nica AC, Ongen H, Irminger JC, et al. Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome [J]. Genome Res,2013,23(9):1554-1562.DOI:10.1101/gr.150706.112.
[8] Beermann J, Piccoli MT, Viereck J, et al. Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches [J]. Physiol Rev, 2016, 96(4):1297-1325.DOI:10.1152/physrev.00041.2015.
[9] Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs[J]. Cell, 2009,136(4):629-641.DOI:10.1016/j.cell.2009.02.006.
[10] Lu Z, Liu N, Wang F. Epigenetic regulations in diabetic nephropathy[J].J Diabetes Res,2017,2017:7805058.DOI:10.1155/2017/7805058.
[11] Li SY, Susztak K.The long noncoding RNA Tug1 connects metabolic changes with kidney disease in podocytes[J].J Clin Invest,2016,126(11):4072-4075.DOI:10.1172/JCI90828.
[12] Mercer TR, Dinger ME, Mattick JS. Long non-coding RNAs:insights into functions [J]. Nat Rev Genet,2009,10( 3):155-159.DOI:10.1038/nrg2521.
[13] Cho YS, Chen CH, Hu C, et al.Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians [J]. Nat Genet,2011,44(1):67-72.DOI:10.1038/ng.1019.
[14] Barrett JC, Clayton DG, Concannon P, et al.Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes [J].Nat Genet,2009,41(6):703-707.DOI:10.1038/ng.381.
[15] Akerman I, Tu Z, Beucher A,et al. Human pancreatic beta cell lncRNAs control cell-specific regulatory networks[J]. Cell Metab,2017,25(2):400-411.DOI:10.1016/j.cmet.2016.11.016.
[16] Zou G, Liu T, Guo L, et al. miR-145 modulates lncRNA-ROR and sox2 expression to maintain human amniotic epithelial stem cell pluripotency and beta islet-like cell differentiation efficiency [J]. Gene, 2016,591(1):48-57.DOI:10.1016/j.gene.2016.06.047.
[17] Arnes L, Akerman I, Balderes DA,et al. βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function[J].Genes Dev,2016,30(5):502-507.DOI:10.1101/gad.273821.115.
[18] Yin DD, Zhang EB, You LH, et al.Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic β cells [J]. Cell Physiol Biochem,2015,35(5):1892-1904.DOI:10.1159/000373999.
[19] Sisino G, Zhou AX, Dahr N, et al.Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro[J].PLoS One,2017,12(8):e0182371.DOI:10.1371/journal.pone.0182371.
[20] Ruan Y, Lin N, Ma Q, et al. Circulating lncRNAs analysis in patients with type 2 diabetes reveals novel genes influencing glucose metabolism and islet β-cell function[J].Cell Physiol Biochem,2018,46(1):335-350. DOI:10.1159/000488434.
[21] Xu B, Gerin I, Miao H, et al.Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity [J].PloS one,2010,5(12):e14199.DOI:10.1371/journal.pone.0014199.
[22] You L, Wang N, Yin D, et al.Downregulation of long noncoding RNA meg3 affects insulin synthesis and secretion in mouse pancreatic beta cells[J].J Cell Physiol,2016,231(4):852-862.DOI:10.1002/jcp.25175.
[23] Wang N, Zhu Y, Xie M, et al.Long noncoding RNA meg3 regulates mafa expression in mouse beta cells by inactivating rad21, smc3 or sin3α[J].Cell Physiol Biochem,2018,45(5):2031-2043.DOI:10.1159/000487983.
[24] Jin F, Wang N,Zhu Y,et al. Downregulation of long noncoding RNA gas5 affects cell cycle and insulin secretion in mouse pancreatic beta cells [J].Cell Physiol Biochem,2017,43(5): 2062-2073.DOI:10.1159/000484191.
[25] Gutschner T, Hämmerle M, Eissmann M, et al. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells[J].Cancer Res,2013,73(3):1180-1189.DOI:10.1158/0008-5472.CAN-12-2850.
[26] Viereck J, Kumarswamy R, Foinquinos A, et al. Long noncoding RNA chast promotes cardiac remodeling[J].Sci Transl Med,2016,8(326):326ra22.DOI:10.1126/scitranslmed.aaf1475.
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