[1]王艳立,张林,胡茂清.长链非编码RNAs与脂肪组织的关系[J].国际内分泌代谢杂志,2017,37(02):131-134.[doi:10.3760/cma.j.issn.1673-4157.2017.02.016]
 Wang Yanli*,Zhang Lin,Hu Maoqing..Relationship between long noncoding RNAs and adipose tissue[J].International Journal of Endocrinology and Metabolism,2017,37(02):131-134.[doi:10.3760/cma.j.issn.1673-4157.2017.02.016]
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长链非编码RNAs与脂肪组织的关系()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年02期
页码:
131-134
栏目:
综述
出版日期:
2017-03-20

文章信息/Info

Title:
Relationship between long noncoding RNAs and adipose tissue
作者:
王艳立张林胡茂清
610075 成都中医药大学临床医学院(王艳立); 610041 成都中医药大学第三附属医院内分泌科,四川省糖尿病防治中心(张林,胡茂清)
Author(s):
Wang Yanli* Zhang Lin Hu Maoqing.
Wang Yanli*, Zhang Lin, Hu Maoqing.
关键词:
长链非编码RNA 脂肪组织 肥胖
Keywords:
Long noncoding RNAs Adipose tissue Obesity
DOI:
10.3760/cma.j.issn.1673-4157.2017.02.016
摘要:
长链非编码RNAs(lncRNAs)是长度大于200个核苷酸而无蛋白编码能力的功能性RNA分子。近年来研究表明,lncRNAs可通过各种机制调控脂肪组织分化形成、功能结构维持及促进白色脂肪组织(WAT)棕色化,特别是对棕色脂肪组织(BAT)的分化成熟发挥重要作用。同时,lncRNAs与肥胖及代谢性疾病的发生、发展密切联系。
Abstract:
Long noncoding RNAs(lncRNAs)are a group of functional RNA molecules longer than 200 nucleotides without protein-coding capacity. Recent studies demonstrated that lncRNAs could regulate adipose tissue differentiation, maintain its function and structure, promote white adipose tissue(WAT)browning by various kinds of mechanisms. Particularly, lncRNAs play important roles in brown adipose tissue(BAT)differentiation and maturation. Besides, lncRNAs are closely associated with the development and progression of obesity and metabolic diseases.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(8167380) 通信作者:胡茂清,Email: hmq63@yeah.net
更新日期/Last Update: 2017-03-20