[1]李洋,任路平,宋光耀.自噬与肝脏脂代谢[J].国际内分泌代谢杂志,2017,37(02):128-130.[doi:10.3760/cma.j.issn.1673-4157.2017.02.015]
 Li Yang*,Ren Luping,Song Guangyao..Autophagy and lipid metabolism in the liver[J].International Journal of Endocrinology and Metabolism,2017,37(02):128-130.[doi:10.3760/cma.j.issn.1673-4157.2017.02.015]
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自噬与肝脏脂代谢()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年02期
页码:
128-130
栏目:
综述
出版日期:
2017-03-20

文章信息/Info

Title:
Autophagy and lipid metabolism in the liver
作者:
李洋任路平宋光耀
050017 石家庄,河北医科大学研究生学院(李洋),内科学教研室(任路平); 050017 石家庄,河北省人民医院内分泌科(任路平,宋光耀)
Author(s):
Li Yang* Ren Luping Song Guangyao.
*Department of Graduate, Hebei Medical University, Shijiazhuang 050017, China
关键词:
自噬 脂代谢 肝脏
Keywords:
Autophagy Lipid metabolism Liver
DOI:
10.3760/cma.j.issn.1673-4157.2017.02.015
摘要:
细胞自噬是利用溶酶体降解受损的细胞器、未折叠蛋白来维持细胞内稳态,在机体生长、发育和衰老中均起重要作用。研究表明,自噬可能与肝脏脂肪合成及分解相关。固醇调节元件结合蛋白通路、转录因子、激素与营养因素可能会影响自噬,从而改变脂代谢。
Abstract:
Autophagy targets cell constituents including damaged organelles, unfolded proteins, to maintain the cellular homeostasis, and it plays an important role in the body's growth, development and aging. Evidences indicate that autophagy may be related to lipogensis and lipolysis in liver. Autophagy may be affected by sterol regulatory element binding protein pathway, transcription factor, hormone, nutritional factors, thereby effects lipid metabolism.

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备注/Memo

备注/Memo:
通信作者:任路平, Email:renluping1122@163.com
更新日期/Last Update: 2017-03-20