[1]黄婧荷,宋焱,郭立新.糖尿病肾脏病的磁共振成像评估方法及进展[J].国际内分泌代谢杂志,2023,43(04):309-312.[doi:10.3760/cma.j.cn121383-20220403-04007]
　Huang Jinghe,Song Yan,Guo Lixin.Magnetic resonance imaging in diabetic kidney disease:assessment and update[J].International Journal of Endocrinology and Metabolism,2023,43(04):309-312.[doi:10.3760/cma.j.cn121383-20220403-04007]
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糖尿病肾脏病的磁共振成像评估方法及进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
43
期数:
2023年04期
页码:
309-312
栏目:
综述
出版日期:
2023-07-20

文章信息/Info

Title:
Magnetic resonance imaging in diabetic kidney disease:assessment and update
作者:
黄婧荷1; 宋焱2; 郭立新1
1北京医院内分泌科 国家老年医学中心 中国医学科学院老年医学研究院,北京 100730; 2北京医院放射科 国家老年医学中心 中国医学科学院老年医学研究院,北京 100730
Author(s):
Huang Jinghe1;  Song Yan2;  Guo Lixin1
1Department of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China; 2Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
关键词:
糖尿病肾脏病;  磁共振成像;  动脉自旋标记;  血氧水平依赖;  扩散加权成像
Keywords:
Diabetic kidney disease;  Magnetic resonance imaging;  Arterial spin labeling;  blood oxygenation level-dependent;  diffusion-weighted imaging
DOI:
10.3760/cma.j.cn121383-20220403-04007
摘要:
糖尿病在全球流行,其中30%～40%的患者会发展为糖尿病肾脏病(DKD)。DKD是发达国家和部分发展中国家终末期肾病的主要原因。该病早期临床不易察觉,若在肾脏出现高灌注、缺氧等病理生理改变后,能早期发现并进行干预,可有效延缓或逆转终末期肾病的结局。近年来,随着磁共振成像(MRI)技术的发展,MRI不仅能够反映肾脏体积及形态学改变,还可在不使用造影剂的情况下,评估肾脏的灌注、氧合、代谢、水分子扩散等与肾脏功能和微观结构相关的改变。本文就MRI在DKD早期诊断、疾病进展监测及药物治疗效果评价中的临床应用作一综述。
Abstract:
Diabetes is prevalent globally, with 30%～40% of patients developing diabetic kidney disease(DKD). DKD is the leading cause of end-stage renal disease in developed and some developing countries. Early clinical detection of this disease is not easy, but pathophysiological changes such as hyperperfusion and hypoxia have occurred in the kidney. If early detection and intervention can be carried out, the outcome of end-stage renal disease may be effectively delayed or reversed. In recent years, with the development of magnetic resonance imaging(MRI)technology, MRI can not only reflect the kidney volume and morphological changes, but also evaluate the kidney perfusion, oxygenation, metabolism, water molecular diffusion and other changes related to kidney function and microstructure without the use of contrast agent. This article reviews the clinical application of MRI in early diagnosis of DKD, monitoring of disease progression and evaluation of drug therapeutic effect.

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备注/Memo

备注/Memo:
通信作者:郭立新,Email: glx1218@163.com; 宋焱,Email: firesong@sina.com
更新日期/Last Update: 2023-08-15