[1]曹白鸽 董艳.母体妊娠期高脂饮食所致的炎性反应状态对子代的影响[J].国际内分泌代谢杂志,2018,38(02):96-98.[doi:10.3760/cma.j.issn.1673-4157.2018.02.006]
　Cao Baige*,Dong Yan..Effects of inflammatory state on offspring induced by maternal high-fat diet during pregnancy[J].International Journal of Endocrinology and Metabolism,2018,38(02):96-98.[doi:10.3760/cma.j.issn.1673-4157.2018.02.006]
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母体妊娠期高脂饮食所致的炎性反应状态对子代的影响()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年02期
页码:
96-98
栏目:
综述
出版日期:
2018-03-20

文章信息/Info

Title:
Effects of inflammatory state on offspring induced by maternal high-fat diet during pregnancy
作者:
曹白鸽 董艳
200092 上海交通大学医学院附属新华医院内分泌科(曹白鸽),儿科研究所(董艳)
Author(s):
Cao Baige*;  Dong Yan.
*Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
关键词:
母体营养;  炎症;  高血压;  肥胖;  非酒精性脂肪性肝病;  糖尿病
Keywords:
Maternal nutrition;  Inflammation;  Hypertension;  Obesity;  Non-alcoholic fatty liver disease;  Diabetes mellitus
DOI:
10.3760/cma.j.issn.1673-4157.2018.02.006
摘要:
母体妊娠期高脂饮食导致自身长期处于慢性炎性反应状态,并且母代高脂饮食所致的炎性反应状态也会在子代的多个组织、器官如脂肪、肝脏和脑等中被激活。这种慢性炎性反应会增加子代高血压、肥胖、非酒精性脂肪性肝炎、糖尿病等的发生率,表明母体妊娠期间高脂饮食所致的慢性炎性反应对子代有很大影响。因此,探讨其作用机制也成为研究的热点。
Abstract:
Maternal high-fat diet during pregnancy leads to long-term chronic inflammation in their own state,which is also activated in many tissues and organs of offspring, including adipose, liver and brain,etc. This chronic inflammation will increase the incidence of hypertension, obesity, non-alcoholic steatohepatitis, diabetes, etc. of offspring, suggesting that inflammation plays an important role in the effects of high-fat diet on offspring during maternal pregnancy. Therefore, exploring its mechanism has also become a hot spot.

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备注/Memo

备注/Memo:

通信作者:董艳,Email:dongyansh@sjtu.edu.cn
更新日期/Last Update: 1900-01-01