[1]王应昉 曹璐 陈凤 许帅 陈风 郭妍 王岩 王涤非.社区老年居民握力体重指数与代谢综合征的相关性[J].国际内分泌代谢杂志,2020,40(01):5-9,15.[doi:10.3760/cma.j.issn.1673-4157.2020.01.002]
　Wang Yingfang,Cao Lu,Chen Feng,et al.Relationship between handgrip strength body mass index and metabolic syndrome in community elderly residents[J].International Journal of Endocrinology and Metabolism,2020,40(01):5-9,15.[doi:10.3760/cma.j.issn.1673-4157.2020.01.002]
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社区老年居民握力体重指数与代谢综合征的相关性()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
40
期数:
2020年01期
页码:
5-9,15
栏目:
论著
出版日期:
2020-01-20

文章信息/Info

Title:
Relationship between handgrip strength body mass index and metabolic syndrome in community elderly residents
作者:
王应昉1 曹璐2 陈凤2 许帅2 陈风1 郭妍1 王岩3 王涤非1
1中国医科大学附属第一医院老年医学内分泌科,沈阳 110001; 2中国医科大学公共卫生学院卫生统计学教研室,沈阳 110013; 3沈阳市铁西区路官社区卫生服务中心 110020
Author(s):
Wang Yingfang1;  Cao Lu2;  Chen Feng2;  Xu Shuai2;  Chen Feng1; Guo Yan1;  Wang Yan3;  Wang Difei1
1 Department of Geriatric Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China; 2Department of Public Health, China Medical University, Shenyang 110013, China; 3Luguan Community Health Service Center, Tiexi Area of Shenyang, Shenyang 110020, China
关键词:
握力体重指数;  代谢综合征
Keywords:
Handgrip strength body mass index;  Metabolic syndrome
DOI:
10.3760/cma.j.issn.1673-4157.2020.01.002
摘要:
目的 探讨握力体重指数与代谢综合征(MS)及其组分的相关性。方法 选取2017年5—10月在沈阳市9个社区卫生服务中心建立健康档案并进行体检的3 598名60岁以上老年常住居民为研究对象,进行问卷调查、体格检测、握力测量和实验室检测,应用Spearman相关分析、logistic回归、受试者工作特征(ROC)曲线分析握力体重指数与MS的相关性。结果 握力体重指数与MS[男性(r=-0.213,P=0.000),女性(r=-0.236,P=0.000)]呈负相关。对不同性别居民握力体重指数水平进行四分位数划分,调整年龄、民族、文化程度、吸烟、饮酒等混杂因素后,随着握力体重指数降低,MS发生的危险性增加。与握力体重指数>P75者相比,男性握力体重指数<P25发生MS的相对危险度为3.714(95% CI:2.604～5.298, P<0.001),P25～P50者为2.816(95% CI:1.997～3.969, P<0.001),P50～P75者为1.655(95% CI:1.169～2.343, P=0.004); 女性握力体重指数<P25者为3.000(95% CI:2.356～3.821, P<0.001),P25～P50者为2.013(95% CI:1.592～2.545, P<0.001),P50～P75者为1.885(95% CI:1.492～2.381, P<0.001)。男性握力体重指数ROC曲线下面积为0.626(0.595～0.657),女性为0.614(0.591～0.637),握力体重指数诊断MS的最佳切点为0.443(男性)及0.351(女性)。结论 握力体重指数与MS及其组分的发生风险呈显著负相关,评估握力体重指数可为MS的预防及早期诊断提供依据。
Abstract:
Objective To investigate the relationship between handgrip strength body mass index and metabolic syndrome and its components.Methods From May to October 2017, a total of 3 598 community residents over 60 years old who had health records and underwent physical examination in nine community health service centers in Shenyang were recruited. All individuals received questionnaires, physical tests, handgrip strength measurement and laboratory tests. Spearman correlation analysis, logistic regression and receiver operating characteristic(ROC)curve were used to analyze the correlation between handgrip strength body mass index and metabolic syndrome.Results Handgrip strength body mass index was negatively correlated with metabolic syndrome[male(r=-0.213, P=0.000), female(r=-0.236, P=0.000)]. Handgrip strength body mass index were divided into quartile for different genders. After adjustment for potential confounders(such as age, nationality, educational level, smoking, drinking), the risks of metabolic syndrome increased with the decrease of handgrip strength body mass index. Compared with individuals with handgrip strength body mass >P75, the relative risk for metabolic syndrome was 3.714(95% CI: 2.604-5.298, P<0.01)in individuals with handgrip strength body mass <P25, 2.816(95% CI: 1.997-3.969, P<0.01)in individuals with P25-P50, and 1.655(95% CI: 1.169-2.343, P=0.004)in individuals with P50-P75 in male, respectively, while the relative risk of metabolic syndrome was 3.000(95% CI: 2.356-3.821, P<0.01)in individuals with handgrip strength body mass <P25, 2.013(95% CI: 1.592-2.545, P<0.01)in individuals with P25-P50, and 1.885(95% CI:1.492-2.381, P<0.01)in individuals with P50-P75 in female, respectively. The area under the ROC curve was 0.626(0.595-0.657)in male, and 0.614(0.591-0.637)in female; the optimal cut-off point for the diagnosis of metabolic syndrome was 0.443 for male and 0.351 for female.Conclusions There is a significant negative correlation between handgrip strength body mass index and the risk of metabolic syndrome and its components. Assessment of handgrip strength body mass index may provide evidence for the prevention and early diagnosis of metabolic syndrome.

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备注/Memo

备注/Memo:
通信作者:王涤非, Email:dfwang@cmu.edu.cn
基金项目:辽宁省中央引导地方科技发展专项(2016007024); 沈阳市科技计划项目(Z18-5-104)
Corresponding author: Wang Difei, Email:dfwang@cmu.edu.cn
Fund program:Local Development Project of Science and Technology Guided by the Central Commission(2016007024); Science and Technology Projects of Shenyang(Z18-5-104)
更新日期/Last Update: 2020-01-20