[1]肖扬 徐书杭 黄华英 郭玲 吕文君 冯宁霞 汪奇峰 茅晓东 陈国芳 刘超.常州地区青少年人群不同代谢综合征诊断标准的比较研究[J].国际内分泌代谢杂志,2020,40(01):1-4.[doi:10.3760/cma.j.issn.1673-4157.2020.01.001]
　Xiao Yang,Xu Shuhang,Huang Huaying,et al.A comparative study of the different diagnostic criteria for metabolic syndrome among adolescents in Changzhou area[J].International Journal of Endocrinology and Metabolism,2020,40(01):1-4.[doi:10.3760/cma.j.issn.1673-4157.2020.01.001]
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常州地区青少年人群不同代谢综合征诊断标准的比较研究()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
40
期数:
2020年01期
页码:
1-4
栏目:
论著
出版日期:
2020-01-20

文章信息/Info

Title:
A comparative study of the different diagnostic criteria for metabolic syndrome among adolescents in Changzhou area
作者:
肖扬1 徐书杭1 黄华英2 郭玲2 吕文君2 冯宁霞2 汪奇峰1 茅晓东1 陈国芳1 刘超1
1南京中医药大学附属中西医结合医院(江苏省中医药研究院)内分泌科 210028; 2常州市武进中医医院内分泌科 213100肖扬、徐书杭对本文有同等贡献
Author(s):
Xiao Yang1;  Xu Shuhang1;  Huang Huaying2;  Guo Ling2;  Lyu Wenjun2;  Feng Ningxia2;  Wang Qifeng1;  Mao Xiaodong1;  Chen Guofang1;  Liu Chao1
1Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, China; 2Department of Endocrinology, Chinese Medical Hospital of Wujin, Changzhou 213100, China
关键词:
青少年;  代谢综合征;  诊断标准
Keywords:
Adolescent;  Metabolic syndrome;  Diagnostic criteria
DOI:
10.3760/cma.j.issn.1673-4157.2020.01.001
摘要:
目的 探讨不同诊断标准对青少年代谢综合征(MS)患病率及各组分检出率的影响。方法 选取江苏省常州市1 097名12～15岁青少年学生(男生占55.6%),进行体格检查和生化检测; 选取3种青少年MS诊断标准,即中华医学会儿科分会推荐的儿童、青少年MS诊断标准(中国标准)、2007年国际糖尿病联盟推荐的诊断标准(IDF标准)和2003年Cook等参照美国国家胆固醇教育计划制定的诊断标准(Cook标准)对受试者进行诊断; 分析中国标准对不同性别青少年人群MS及各组分的检出率; 比较3种不同诊断标准下的青少年MS患病率、各组分检出率的差异。结果 中国标准检出的青少年MS患病率男性显著高于女性(χ2=9.574,P=0.002)。MS组分中,男性肥胖(χ2=30.211,P<0.01)、高血压、高血糖、低高密度脂蛋白-胆固醇血症的检出率均高于女性。中国标准检出率最高的MS组分是高甘油三酯血症(χ2=177.34,P<0.01),而IDF标准(χ2=237.43,P<0.01)和Cook标准(χ2=352.11,P<0.01)检出率最高的均为高血压。结论 3种诊断标准对青少年MS总体患病率的检出结果差别较小,而对MS各组分检出率差别显著。
Abstract:
Objective To explore the impact of different diagnostic criteria on the prevalence of metabolic syndrome(MS)and the detection rate of its components among adolescents.Methods A total of 1 097 middle school students aged between 12-15 years old(55.6% males)in Changzhou area of Jiangsu Province were enrolled. All the participants underwent physical examination and biochemical test, and MS was diagnosed with 3 different criteria: children and teenagers MS diagnostic criteria recommended by Pediatric Academy of Chinese Medical Association(Chinese criteria), the International Diabetes Federation criteria in 2007(IDF criteria)or Cook criteria based on the National Cholesterol Education Program-Adult Treatment Panel in 2003(Cook criteria). The detection rate of MS and its components in adolescent population of different genders were analyzed with Chinese criteria, and also the detection rate of teenage MS and its components were compared under three different diagnostic criteria.Results The detection rate of teenage MS in male was significantly higher than that in female with Chinese criteria(χ2=9.574, P=0.002). Among the components of MS, the detection rate of obesity(χ2=30.211, P<0.01), hypertension, hyperglycemia, and low high-density lipoprotein-cholesterol in male subjects were all higher than those in female subjects. The component with the highest incidence was hypertriglyceridemia with Chinese criteria(χ2=177.34, P<0.01), and hypertension with IDF criteria(χ2=237.43, P<0.01)and Cook criteria(χ2=352.11, P<0.01).Conclusions Three diagnostic criteria show little difference in the overall prevalence of MS among teenagers. However, the detection rate of MS components are evidently different with three criteria.

参考文献/References:

[1] Singh GK. Metabolic syndrome in children and adolescents[J].Curr Treat Options Cardiovasc Med,2006,8(5):403-413.DOI:10.1007/s11936-006-0045-3.
[2] 中华医学会儿科学分会内分泌遗传代谢学组,中华医学会儿科学分会心血管学组, 中华医学会儿科学分会儿童保健学组.中国儿童青少年代谢综合征定义和防治建议[J].中华儿科杂志,2012,50(6):420-422.DOI:10.3760/cma.j.issn.0578-1310.2012.06.005.
[3] Zimmet P,Alberti G,Kaufman F,et al.The metabolic syndrome in children and adolescents[J].Lancet,2007,369(9579):2059-2061.DOI:10.1016/S0140-6736(07)60958-1.
[4] Cook S,Weitzman M,Auinger P,et al.Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994[J].Arch Pediatr Adolesc Med,2003,157(8):821-827.DOI:10.1001/archpedi.157.8.821.
[5] 中国肥胖问题工作组.中国成人超重和肥胖症预防与控制指南(节录)[J]. 营养学报,2004,26(1):1-4.DOI:10.13325/j.cnki.acta.nutr.sin.2004.01.001.
[6] Agudelo GM,Bedoya G,Estrada A,et al. Variations in the prevalence of metabolic syndrome in adolescents according to different criteria used for diagnosis: which definition should be chosen for this age group?[J].Metab Syndr Relat Disord,2014,12(4):202-209.DOI:10.1089/met.2013.0127.
[7] Magge SN, Goodman E, Armstrong SC,et al. The metabolic syndrome in children and adolescents:shifting the focus to cardiometabolic risk factor clustering[J].Pediatrics,2017,140(2):pii:e20171603.DOI:10.1542/peds.2017-1603.
[8] 何宇纳, 赵文华, 赵丽云,等.2010-2012年中国10-17岁儿童青少年代谢综合征流行情况[J].中华预防医学杂志,2017,51(6):513-518. DOI:10.3760/cma.j.issn.0253-9624.2017.06.011.
[9] 叶佩玉, 闫银坤, 丁文清,等.中国儿童青少年代谢综合征患病率Meta分析[J].中华流行病学杂志,2015,36(8):884-888.DOI:10.3760/cma.j.issn.0254-6450.2015.08.025.
[10] 儿童代谢综合征中国工作组.中国六城市学龄儿童代谢综合征流行现状研究[J].中华儿科杂志,2013,51(6):409-413.DOI:10.3760/cma.j.issn.0578-1310.2013.06.004.
[11] 李韵,唐向东.儿童和青少年睡眠长度与代谢综合征[J].中华医学杂志,2014,94(34):2713-2715.DOI:10.3760/cma.j.issn.0376-2491.2014.34.018.
[12] 厉平,郭超,李雪,等.三种不同代谢综合征诊断标准对辽阳市青少年人群诊断能力的比较[J].中华内分泌代谢杂志,2017,33(2):93-97.DOI:10.3760/cma.j.issn.1000-6699.2017.02.001.

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备注/Memo

备注/Memo:
通信作者:黄华英,Email:whfhhyfeifan@sina.com; 刘超,Email:liuchao@nfmcn.com
基金项目:常州市武进区科技项目(WS201617); 国家重点研发计划(2016YFC1305202)
Xiao Yang, Xu Shuhang contributed equally to this article
Corresponding author: Huang Huaying, Email:whfhhyfeifan@sina.com; Liu Chao, Email:liuchao@nfmcn.com
更新日期/Last Update: 2020-01-20