参考文献/References:
[1] Hsuchou H, Pan W, Kastin AJ. The fasting polypeptide FGF21 can enter brain from blood[J].Peptides,2007,28(12):2382-2386.DOI:10.1016/j.peptides.2007.10.007.
[2] Itoh N,Ornitz DM. Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease[J].J Biochem,2011,149(2):121-130.DOI:10.1093/jb/mvq121.
[3] Beenken A,Mohammadi M. The FGF family: biology, pathophysiology and therapy[J].Nat Rev Drug Discov,2009,8(3):235-253.DOI:10.1038/nrd2792.
[4] Ma B, Cheng DS, Xia ZF,et al. Randomized, multicenter, double-blind, and placebo-controlled trial using topical recombinant human acidic fibroblast growth factor for deep partial-thickness burns and skin graft donor site[J].Wound Repair Regen,2007,15(6):795-799.DOI:10.1111/j.1524-475X.2007.00307.x.
[5] Jonker JW,Suh JM,Atkins AR,et al.A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis[J].Nature,2012,485(7398):391-394.DOI:10.1038/nature10998.
[6] Suh JM,Jonker JW,Ahmadian M,et al.Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer[J].Nature,2014,513(7518):436-439.DOI:10.1038/nature13540.
[7] Perry RJ,Lee S,Ma L,et al.FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenalaxis[J].Nat Commun,2015,6:6980.DOI:10.1038/ncomms7980.
[8] Wang S,Yang Q,Yu S,et al.Fibroblast growth factor 1 levels are elevated in newly diagnosed type 2 diabetes compared to normal glucose tolerance controls[J].Endocr J,2016,63(4):359-365. DOI:10.1507/endocrj.EJ15-0627.
[9] 孟庆杰,黄保荣,陈贤云,等.FGF1 基因多态性与 2 型糖尿病脂代谢的相关性[J].广东医学,2015,36(18): 2856-2858.
[10] Scarlett JM,Rojas JM,Matsen ME,et al.Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents[J].Nat Med,2016,22(7):800-806.DOI:10.1038/nm.4101.
[11] Kurosu H,Choi M,Ogawa Y,et al.Tissue-specific expression of betaKlotho and fibroblast growth factor(FGF)receptor isoforms determines metabolic activity of FGF19 and FGF21[J].J Biol Chem,2007,282(37):26687-26695.DOI:10.1074/jbc.M704165200.
[12] Wu X,Ge H,Gupte J,et al.Co-receptor requirements for fibroblast growth factor-19 signaling[J].J Biol Chem,2007,282(40):29069-29072.DOI:10.1074/jbc.C700130200.
[13] Kurosu H,Ogawa Y,Miyoshi M,et al.Regulation of fibroblast growth factor-23 signaling by klotho[J].J Biol Chem,2006,281(10):6120-6123.DOI:10.1074/jbc.C500457200.
[14] Kir S,Beddow SA,Samuel VT,et al.FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis[J].Science,2011,331(6024):1621-1624. DOI:10.1126/science.1198363.
[15] Potthoff MJ,Boney-Montoya J,Choi M,et al.FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway[J].Cell Metab,2011,13(6):729-738.DOI:10.1016/j.cmet.2011.03.019.
[16] Donate-Correa J,Martín-Nún~ez E,Delgado NP,et al.Implications of fibroblast growth factor/Klotho system in glucose metabolism and diabetes[J].Cytokine Growth Factor Rev,2016,28:71-77.DOI:10.1016/j.cytogfr.2015.12.003.
[17] Wei W,Dutchak PA,Wang X,et al.Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ[J].Proc Natl Acad Sci U S A,2012,109(8):3143-3148.DOI:10.1073/pnas.1200797109.
[18] Markan KR,Potthoff MJ.Metabolic fibroblast growth factors(FGFs): mediators of energy homeostasis[J].Semin Cell Dev Biol,2016,53:85-93.DOI:10.1016/j.semcdb.2015.09.021.
[19] Ezumba I,Quarles LD,Kovesdy CP.FGF23 and the heart[J].G Ital Nefrol,2014,31(6). pii: gin/31.6.12.
[20] Emanuelli B,Vienberg SG,Smyth G,et al.Interplay between FGF21 and insulin action in the liver regulates metabolism[J].J Clin Invest,2014,124(2):515-527.DOI:10.1172/JCI67353.
[21] Xu J,Stanislaus S,Chinookoswong N,et al.Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects[J].Am J Physiol Endocrinol Metab,2009,297(5):E1105-1114.DOI:10.1152/ajpendo.00348.2009.
[22] Smith R,Duguay A,Weiszmann J,et al.A novel approach to improve the function of FGF21[J].BioDrugs,2013,27(2):159-166.DOI:10.1007/s40259-013-0013-x.
[23] So WY, Leung PS. Fibroblast growth factor 21 as an emerging therapeutic target for type 2 diabetes mellitus[J].Med Res Rev,2016,36(4):672-704. DOI:10.1002/med.21390.
[24] Cheng X,Zhu B,Jiang F,et al.Serum FGF-21 levels in type 2 diabetic patients[J].Endocr Res,2011,36(4):142-148.DOI:10.3109/07435800.2011.558550.
[25] 孙小蒙,范慧,张恒,等.初诊 2 型糖尿病患者血浆成纤维细胞生长因子21水平与相关因素[J].中华糖尿病杂志,2014,6(10):730-733.DOI:10.3760/cma.j.issn.1674-5809.2014.10.006.
[26] Wang B,Yang G,Yang M,et al. Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM[J].Cytokine,2012,57(2):300-303.DOI:10.1016/j.cyto.2011.11.002.
[27] Yang M,Dong J,Liu H,et al. Effects of short-term continuous subcutaneous insulin infusion on fasting plasma fibroblast growth factor-21 levels in patients with newly diagnosed type 2 diabetesmellitus[J].PLoS One,2011,6(10):e26359.DOI:10.1371/journal.pone.0026359.
[28] Zibar K,Blaslov K,Bulum T, et al. Basal and postprandial change in serum fibroblast growth factor-21 concentration in type 1 diabetic mellitus and in healthy controls[J].Endocrine,2015,48(3):848-855.DOI:10.1007/s12020-014-0413-9.
[29] Xiao Y,Xu A,Law LS,et al.Distinct changes in serum fibroblast growth factor 21 levels in different subtypes of diabetes[J].J Clin Endocrinol Metab,2012,97(1):E54-E58.DOI:10.1210/jc.2011-1930.
[30] 孙国鹏,叶贤龙,任桂萍,等. 成纤维细胞生长因子21对1型糖尿病动物模型的肝糖代谢影响及机制研究[J]. 生物化学与生物物理进展,2011, 38(10): 953-960.
[31] Sonne DP,van Nierop FS,Kulik W,et al.Postprandial plasma concentrations of individual bile acids and FGF-19 in patients with type 2 diabetes[J].J Clin Endocrinol Metab,2016,101(8):3002-3009.DOI:10.1210/jc.2016-1607.
[32] Barutcuoglu B,Basol G,Cakir Y,et al.Fibroblast growth factor-19 levels in type 2 diabetic patients with metabolic syndrome[J].Ann Clin Lab Sci,2011,41(4):390-396.
[33] Gerhard GS,Styer AM,Wood GC,et al.A role for fibroblast growth factor 19 and bile acids in diabetes remission after Roux-en-Y gastric bypass[J].Diabetes Care,2013,36(7):1859-1864.DOI:10.2337/dc12-2255.
[34] Morton GJ,Matsen ME,Bracy DP,et al.FGF19 action in the brain induces insulin-independent glucose lowering[J].J Clin Invest,2013,123(11):4799-4808.DOI:10.1172/Jci70710.
[35] Shimada T,Urakawa I,Isakova T,et al.Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active[J].J Clin Endocrinol Metab,2010,95(2):578-585. DOI:10.1210/jc.2009-1603.
[36] Freedman BI,Divers J,Russell GB,et al.Plasma FGF23 and calcified atherosclerotic plaque in african americans with type 2 diabetes mellitus[J].Am J Nephrol,2015,42(6):391-401.DOI:10.1159/000443241.
[37] Biscetti F,Straface G,Pitocco D,et al.Fibroblast growth factor 23 serum level in type 2 diabetic italian subjects with peripheral arterial disease and critical limb ischemia[J].Eur Rev Med Pharmacol Sci,2016,20(19):4048-4054.
[38] He X,Hu X,Ma X,et al.Elevated serum fibroblast growth factor 23 levels as an indicator of lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus[J].Cardiovasc Diabetol,2017,16(1):77.DOI:10.1186/s12933-017-0559-x.
[39] Winther K,Nybo M,Vind B,et al.Acute hyperinsulinemia is followed by increased serum concentrations of fibroblast growth factor 23 in type 2 diabetes patients[J].Scand J Clin Lab Invest,2012,72(2):108-113.DOI:10.3109/00365513.2011.640407.
[40] Reyes-Garcia R, Garcia-Martín A, García-Fontana B,et al. FGF23 in type 2 diabetic patients: relationship with bone metabolism and vascular disease[J].Diabetes Care,2014,37(5):e89-e90.DOI:10.2337/dc13-2235.
[41] Hu X, Ma X, Luo Y,et al. Elevation in fibroblast growth factor 23 and its value for identifying subclinical atherosclerosis in first-degree relatives of patients with diabetes[J].Sci Rep,2016,6:34696. DOI:10.1038/srep34696.
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