[1]高晶扬,张曼娜,曲伸.microRNA与脂肪组织慢性低度炎性反应[J].国际内分泌代谢杂志,2017,37(02):135-138.[doi:10.3760/cma.j.issn.1673-4157.2017.02.017]
　Gao Jingyang,Zhang Manna,Qu Shen..microRNA and chronic low-grade inflammation of adipose tissue[J].International Journal of Endocrinology and Metabolism,2017,37(02):135-138.[doi:10.3760/cma.j.issn.1673-4157.2017.02.017]
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microRNA与脂肪组织慢性低度炎性反应()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年02期
页码:
135-138
栏目:
综述
出版日期:
2017-03-20

文章信息/Info

Title:
microRNA and chronic low-grade inflammation of adipose tissue
作者:
高晶扬; 张曼娜; 曲伸
200072 上海,同济大学附属第十人民医院内分泌科
Author(s):
Gao Jingyang;  Zhang Manna;  Qu Shen.
Department of Endocrinology, The Tenth People's Hospital of Shanghai, Tongji University, Shanghai 200072, China
关键词:
慢性低度炎症;  microRNA;  脂肪组织;  炎症因子
Keywords:
Chronic low-grade inflammation;  MicroRNA;  Lipid metabolism;  Inflammatory cytokines
DOI:
10.3760/cma.j.issn.1673-4157.2017.02.017
摘要:
脂肪组织慢性低度炎性反应是肥胖、2型糖尿病、高血压、心血管疾病等代谢性疾病的中心环节。研究脂肪组织慢性低度炎性反应的精确调控过程,对于预防和治疗肥胖及相关疾病有重要意义。microRNA是一类非编码RNA,具有调节基因表达的功能。研究显示,microRNA对脂肪组织巨噬细胞、经典炎性反应信号通路及炎性因子、抗炎因子等具有调控作用。
Abstract:
Chronic low-grade inflammation in adipose tissue is the central link of obesity, type 2 diabetes, hypertension, cardiovascular disease and other metabolic diseases. It is important to study the regulation of chronic low-grade inflammation in adipose tissue, which will help us to prevent and treat obesity and related diseases. MicroRNA is a class of small non-coding RNA, and is responsible for the regulation of gene expression.Studies show that miRNA could regulate macrophage, classical inflammatory signaling pathway and inflammatory factors and anti-inflammatory factors.

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备注/Memo

备注/Memo:
通信作者:张曼娜,Email: mannazhang@126.com
更新日期/Last Update: 2017-03-20