[1]张蕴南,相萍萍,刘超.限食通过调控表观遗传修饰改善代谢综合征的研究进展[J].国际内分泌代谢杂志,2022,42(05):364-368.[doi:10.3760/cma.j.cn121383-20210622-06055]
 Zhang Yunnan,Xiang Pingping,Liu Chao..Dietary restriction reversing metabolic syndrome by regulating epigenetic modifications[J].International Journal of Endocrinology and Metabolism,2022,42(05):364-368.[doi:10.3760/cma.j.cn121383-20210622-06055]
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限食通过调控表观遗传修饰改善代谢综合征的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年05期
页码:
364-368
栏目:
综述
出版日期:
2022-09-20

文章信息/Info

Title:
Dietary restriction reversing metabolic syndrome by regulating epigenetic modifications
作者:
张蕴南相萍萍刘超
南京中医药大学附属中西医结合医院内分泌科 210028
Author(s):
Zhang Yunnan Xiang Pingping Liu Chao.
Department of Endocrinology, the Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, China
关键词:
饮食限制 代谢综合征 肥胖 表观遗传修饰
Keywords:
Dietary restriction Metabolic syndrome Obesity Epigenetic modification
DOI:
10.3760/cma.j.cn121383-20210622-06055
摘要:
代谢综合征患病率逐年增高,已成为危害人类健康的重要疾病。基因与环境的相互作用是造成本病发生发展的重要原因。饮食限制作为一种有效的治疗手段可显著改善代谢综合征。现有证据表明,表观遗传修饰在限食疗法改善代谢综合征的过程中发挥重要的作用。本文通过分析代谢综合征与表观遗传修饰之间的关系,以及饮食限制改善代谢综合征的表观遗传调控方式,阐明表观遗传机制在代谢综合征的诊断与预后中的潜在用途。
Abstract:
The incidence of metabolic syndrome has increased significantly in recent years, and it has become a major disease endangering human health. The interaction between genes and environment is an important reason for the occurrence and development of this disease. Dietary restriction as an effective treatment can improve metabolic syndrome, and epigenetic modification plays an important role in this process. This article analyzes the relationship between metabolic syndrome and epigenetic modification, and clarifies the potential use of epigenetic mechanisms in the diagnosis and prognosis of metabolic syndrome.

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通信作者:刘超,liuchao@nfmcn.com
更新日期/Last Update: 2022-09-10