[1]赵先鹏.Wolfram综合征的治疗进展[J].国际内分泌代谢杂志,2021,41(05):430-433.[doi:10.3760/cma.j.cn121383-20200609-06022]
　Zhao Xianpeng..Research progress of Wolfram syndrome[J].International Journal of Endocrinology and Metabolism,2021,41(05):430-433.[doi:10.3760/cma.j.cn121383-20200609-06022]
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Wolfram综合征的治疗进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
41
期数:
2021年05期
页码:
430-433
栏目:
“特殊类型糖尿病”专题
出版日期:
2021-09-30

文章信息/Info

Title:
Research progress of Wolfram syndrome
作者:
赵先鹏
博爱县中医院内科,焦作 454450
Author(s):
Zhao Xianpeng.
Department of Internal Medicine Boai Hospital of Traditional Chinese Medicine, Jiaozuo 454450, China
关键词:
Wolfram综合征;  诊断;  基因治疗
Keywords:
Wolfram syndrome;  Diagnosis;  Gene therapy
DOI:
10.3760/cma.j.cn121383-20200609-06022
摘要:
Wolfram综合征(WS)是一种罕见的遗传疾病,该病预后极差,传统观念认为尚无阻止或逆转此病进展的治疗方式。近年来发现,产前筛查与预防、早期诊断、多学科协作以及针对性治疗对WS病程的延缓和逆转有较大意义。因此,基于国内外现有文献研究,对WS的分型、临床表现、鉴别诊断进行综述,重点对近年来WS的治疗方法进行总结,为临床诊疗提供参考。
Abstract:
Wolfram syndrome(WS)is a rare genetic disease with poor prognosis. In the past, there has been no treatment to prevent or reverse the progression of the disease. Antenatal screening, early diagnosis, multidisciplinary collaboration and targeted therapy have been found to be of great significance in delaying and reversing the course of WS disease in recent years. So, WS classification, clinical manifestations and differential diagnosis are reviewed in this paper, with emphasis on the analysis and summary of WS treatment methods, in order to provide reference for clinical diagnosis and treatment of WS.

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备注/Memo

备注/Memo:
通信作者:赵先鹏,Email:1620194763@qq.com
更新日期/Last Update: 2021-10-10