[1]林玲 林真 徐一娇 滕菁.多能干细胞向甲状腺滤泡细胞的诱导分化[J].国际内分泌代谢杂志,2018,38(06):397-400.[doi:10.3760/cma.j.issn.1673-4157.2018.06.009]
 Lin Ling*,Lin Zhen,Xu Yijiao,et al.Inducing differentiation of pluripotent stem cells into thyroid follicular cells[J].International Journal of Endocrinology and Metabolism,2018,38(06):397-400.[doi:10.3760/cma.j.issn.1673-4157.2018.06.009]
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多能干细胞向甲状腺滤泡细胞的诱导分化()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年06期
页码:
397-400
栏目:
综述
出版日期:
2018-11-20

文章信息/Info

Title:
Inducing differentiation of pluripotent stem cells into thyroid follicular cells
作者:
林玲 林真 徐一娇 滕菁
作者单位:361000 厦门市中医院检验科(林玲、林真、滕菁); 210028 南京中医药大学附属中西医结合医院内分泌代谢病院区(徐一娇)
Author(s):
Lin Ling* Lin Zhen Xu Yijiao Teng Jing
*Medical Laboratory, Traditional Chinese Medicine Hospital, Xiamen 361000, China
关键词:
多能干细胞 诱导 分化 甲状腺滤泡细胞
Keywords:
Pluripotent stem cells Induce Differentiation Thyroid follicular cells
DOI:
10.3760/cma.j.issn.1673-4157.2018.06.009
摘要:
多能干细胞(PSCs)是一种特殊的干细胞群,具有自我更新、无限增殖和向3个胚层多向分化的潜能。PSCs包括胚胎干细胞和诱导多能干细胞,为疾病模型的构建、细胞替代性治疗和药物研发等方面,提供了无限的细胞来源。近期,PSCs通过3-D培养形成甲状腺类器官的研究已成为热点,这项技术基于PSCs向甲状腺滤泡细胞的诱导分化。
Abstract:
Pluripotent stem cells(PSCs)are a special group of stem cells characterized by their capability to self-renew, infinite proliferation and the potential to differentiate into all derivative cell types of the three germ layers. PSCs, including embryonic stem cells and induced pluripotent stem cells, provide a unlimited cell source to build disease modeling, study cell-replacement therapy and facilitate drug discovery. Recently, thyroid organoids, generated from PSCs through the development of three-dimensional culture systems, have become a hot topic. This technology builds upon a foundation of inducing PSCs.

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备注/Memo

备注/Memo:
作者单位:361000 厦门市中医院检验科(林玲、林真、滕菁); 210028 南京中医药大学附属中西医结合医院内分泌代谢病院区(徐一娇)
通信作者:滕菁,Email:tengjing1108@126.com
更新日期/Last Update: 2018-12-30