参考文献/References:
[1] Choe SS,Huh JY, Hwang IJ,et al. Adipose tissue remodeling: its role in energy metabolism and metabolic disorders[J].Front Endocrinol(Lausanne),2016,7:30.DOI:10.3389/fendo.2016.00030.
[2] Lee BC,Lee J.Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance[J].Biochim Biophys Acta,2014,1842(3):446-462.DOI:10.1016/j.bbadis.2013.05.017.
[3] Mirabeau O,Perlas E,Severini C,et al.Identification of novel peptide hormones in the human proteome by hidden Markov model screening[J].Genome Res,2007,17(3):320-327.DOI:10.1101/gr.5755407.
[4] Sonmez K,Zaveri NT,Kerman IA,et al.Evolutionary sequence modeling for discovery of peptide hormones[J].PLoS Comput Biol,2009,5(1):e1000258.DOI:10.1371/journal.pcbi.1000258.
[5] Walewski JL,Ge F,Gagner M,et al.Adipocyte accumulation of long-chain fatty acids in obesity is multifactorial, resulting from increased fatty acid uptake and decreased activity of genes involved in fat utilization[J].Obes Surg,2010,20(1):93-107.DOI:10.1007/s11695-009-0002-9.
[6] Walewski JL,Ge F,Lobdell H 4th,et al.Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity[J].Obesity(Silver Spring),2014,22(7):1643-1652.DOI:10.1002/oby.20725.
[7] Ge JF,Walewski JL,Anglade D,et al.Regulation of hepatocellular fatty acid uptake in mouse models of fatty liver disease with and without functional leptin signaling: roles of NfKB and SREBP-1C and the effects of spexin[J].Semin Liver Dis,2016,36(4):360-372.DOI:10.1055/s-0036-1597248.
[8] Kim DK,Yun S,Son GH,et al.Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galaninreceptor type Ⅱ and Ⅲ[J].Endocrinology,2014,155(5):1864-1873. DOI:10.1210/en.2013-2106.
[9] Ma A,He M,Bai J,et al.Dual role of insulin in spexin regulation: functional link between food intake and spexin expression in a fish model[J].Endocrinology,2017,158(3):560-577.DOI:10.1210/en.2016-1534.
[10] Yang YH,Manning Fox JE,Zhang KL,et al.Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion[J].Proc Natl Acad Sci U S A,2013,110(41):16480-16485.DOI:10.1073/pnas.1214312110.
[11] Glawe JD,Mijalis EM,Davis WC,et al.SDF-1-CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1-SLIT2 interactions in mice[J].Diabetologia,2013,56(10):2222-2230.DOI:10.1007/s00125-013-2978-x.
[12] Svensson KJ,Long JZ,Jedrychowski MP,et al. A secreted Slit2 fragment regulates adipose tissue thermogenesis and metabolic function[J].Cell Metab,2016,23(3):454-466.DOI:10.1016/j.cmet.2016.01.008.
[13] Yamaguchi N,Argueta JG,Masuhiro Y,et al.Adiponectin inhibits Toll-like receptor family-induced signaling[J].FEBS Lett,2005,579(30):6821-6826. DOI:10.1016/j.febslet.2005.11.019.
[14] Enomoto T,Ohashi K,Shibata R,et al.Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism[J].J Biol Chem,2011,286(40):34552-34558.DOI:10.1074/jbc.M111.277319.
[15] Wei Z,Peterson JM,Lei X,et al.C1q/TNF-related protein-12(CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes[J].J Biol Chem,2012,287(13):10301-10315.DOI:10.1074/jbc.M111.303651.
[16] Gray S,Wang B,Orihuela Y,et al.Regulation of gluconeogenesis by Krüppel-like factor 15[J].Cell Metab,2007,5(4):305-312.DOI:10.1016/j.cmet.2007.03.002.
[17] Enomoto T,Ohashi K,Shibata R,et al.Transcriptional regulation of an insulin-sensitizing adipokine adipolin/CTRP12 in adipocytes by Krüppel-like factor 15[J].PLoS One,2013,8(12):e83183.DOI:10.1371/journal.pone.0083183.
[18] Dahlman I,Elsen M,Tennagels N,et al.Functional annotation of the human fat cell secretome[J].Arch Physiol Biochem,2012,118(3):84-91.DOI:10.3109/13813455.2012.685745.
[19] Hammarstedt A,Hedjazifar S,Jenndahl L,et al.WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4[J].Proc Natl Acad Sci U S A,2013,110(7):2563-2568.DOI:10.1073/pnas.1211255110.
[20] Chowdhury S,Wang X,Srikant CB,et al.IGF-I stimulates CCN5/WISP2 gene expression in pancreatic β-cells, which promotes cell proliferation and survival against streptozotocin[J]. Endocrinology,2014,155(5):1629-1642.DOI:10.1210/en.2013-1735.
[21] Almario RU,Karakas SE.Roles of circulating WNT-signaling proteins and WNT-inhibitors in human adiposity, insulin resistance, insulin secretion, and inflammation[J]. Horm Metab Res,2015,47(2):152-157.DOI:10.1055/s-0034-1384521.
[22] Grünberg JR,Hoffmann JM,Hedjazifar S,et al.Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance[J].Sci Rep,2017,7:43515.DOI:10.1038/srep43515.
[23] Chakraborty A,Koldobskiy MA,Bello NT,et al.Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain[J].Cell,2010,143(6):897-910.DOI:10.1016/j.cell.2010.11.032.
[24] Ghoshal S,Zhu Q,Asteian A,et al.TNP[N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway[J].Mol Metab,2016,5(10):903-917.DOI:10.1016/j.molmet.2016.08.008.
[25] Ghoshal S,Tyagi R,Zhu Q,et al.Inositol hexakisphosphate kinase-1 interacts with perilipin1 to modulate lipolysis[J].Int J Biochem Cell Biol,2016,78:149-155. DOI:10.1016/j.biocel.2016.06.018.
[26] Boregowda SV,Ghoshal S,Booker CN,et al.IP6K1 reduces mesenchymal stem/stromal cell fitness and potentiates high fat diet-induced skeletal involution[J].Stem Cells,2017,35(8):1973-1983.DOI:10.1002/stem.2645.
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