[1]吕丹 李晓思 陈树春 王泽普.Betatrophin:糖尿病再生治疗的新希望[J].国际内分泌代谢杂志,2015,(05):351-353.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.016]
 Lyu Dan*,Li Xiaosi,Chen Shuchun,et al.Betatrophin:new hope for regeneration therapy of diabetes[J].International Journal of Endocrinology and Metabolism,2015,(05):351-353.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.016]
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Betatrophin:糖尿病再生治疗的新希望()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年05期
页码:
351-353
栏目:
基础研究
出版日期:
2015-09-20

文章信息/Info

Title:
Betatrophin:new hope for regeneration therapy of diabetes
作者:
吕丹 李晓思 陈树春 王泽普
050017 石家庄,河北医科大学研究生学院(吕丹,李晓思,王泽普); 050051 石家庄,河北医科大学研究生学院内科学教研室,河北省人民医院内分泌一科(陈树春)
Author(s):
Lyu Dan*Li XiaosiChen ShuchunWang Zepu.
*Graduate School of Hebei Medical University, Shijiazhuang 050017,China
关键词:
Betatrophin β细胞增殖 糖尿病
Keywords:
Betatrophin Beta cells proliferation Diabetes mellitus
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.05.016
摘要:
肝源性因子betatrophin可特异性的引起胰岛β细胞增殖。动物研究已证实betatrophin诱导增殖的β细胞具有正常功能。人体研究也发现糖尿病患者体内betatrophin水平升高,并且与胰岛素抵抗相关,这可能是一种代偿性反应,但其具体机制并不清楚。因此进一步研究betatrophin与糖尿病的关系可为糖尿病的再生治疗带来希望。
Abstract:
Hepatogenic factor betatrophin can cause islet β cells proliferation specifically. Animal studies have confirmed that proliferative β cells induced by betatrophin have normal function. Studies in human also found that betatrophin level is elevated in patients with diabetes and is associated with insulin resistance. It may be a compensatory response, but the specific mechanism is unclear. Therefore, further research of the relationship between betatrophin and diabetes may provide hope for the regeneration therapy of diabetes.

参考文献/References:

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相似文献/References:

[1]严克敏,龚凤英.Betatrophin与胰岛β细胞增殖及糖脂代谢的关系[J].国际内分泌代谢杂志,2016,36(04):253.[doi:10.3760/cma.j.issn.1673-4157.2016.04.10]
 Yan Kemin,Gong Fengying.Relationships between betatrophin, islet β cell proliferation and glucose-lipid metabolism[J].International Journal of Endocrinology and Metabolism,2016,36(05):253.[doi:10.3760/cma.j.issn.1673-4157.2016.04.10]

备注/Memo

备注/Memo:
作者单位:050017 石家庄,河北医科大学研究生学院(吕丹,李晓思,王泽普); 050051 石家庄,河北医科大学研究生学院内科学教研室,河北省人民医院内分泌一科(陈树春) 通信作者:陈树春,Email:guang6701@sina.com
更新日期/Last Update: 2015-09-20