[1]孙洪平,陈国芳,曹雯,等.糖尿病与甲状腺癌关系的研究进展[J].国际内分泌代谢杂志,2014,(02):90-94.[doi:10.3760/cma.j.issn.1673-4157.2014.02.006]
 Sun Hongping,Chen Guofang,Cao Wen,et al.Diabetes and thyroid cancer[J].International Journal of Endocrinology and Metabolism,2014,(02):90-94.[doi:10.3760/cma.j.issn.1673-4157.2014.02.006]
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糖尿病与甲状腺癌关系的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年02期
页码:
90-94
栏目:
甲状腺疾病专栏
出版日期:
2014-04-30

文章信息/Info

Title:
Diabetes and thyroid cancer
作者:
孙洪平陈国芳曹雯狄红杰刘超
210028 南京,中国中医科学院江苏分院,南京中医药大学附属中西医结合医院内分泌代谢院区   
Author(s):
Sun HongpingChen GuofangCao WenDi Hongjie Liu Chao.
Endocrine and Diabetes Center,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing University of Traditional Chinese Medicine,Jiangsu Branch of China Academy of Chinese Medical Science,Nanjing 210028,China Corresponding author:
关键词:
糖尿病甲状腺癌
Keywords:
Diabetes mellitusThyroid cancer
DOI:
10.3760/cma.j.issn.1673-4157.2014.02.006
摘要:
糖尿病患者甲状腺癌的发病风险明显增加,主要的危险因素包括胰岛素抵抗、肥胖、高血糖及高血脂、促甲状腺激素水平升高、降糖药物如胰岛素和磺脲类药物以及维生素D缺乏等。上述因素通过如胰岛素样生长因子-1、cAMP/蛋白激酶A及氧化应激等信号通路促进甲状腺癌的发生、发展。
Abstract:
The incidence of thyroid cancer in patients with diabetes is significantly increased,which happens possibly through insulin resistance,obesity,high blood glucose and high triglyceride,elevated levels of thyroid stimulating hormone(TSH),antidiabetic therapy including insulin and sulfonylureas as well as vitamin D deficiency. All the above factors take part in the occurrence and development of thyroid cancer through different signal pathway such as insulin-like growth factor-1,cAMP/protein kinase A and oxidative stress.

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备注/Memo

备注/Memo:
通信作者:刘超,Email:liuchao@nfmcn.com
更新日期/Last Update: 2014-03-20