[1]张晓燕,陈莉明.儿童非酒精性脂肪性肝病研究进展[J].国际内分泌代谢杂志,2007,(04):289-292.
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儿童非酒精性脂肪性肝病研究进展
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2007年04期
页码:
289-292
栏目:
综述
出版日期:
2007-08-20

文章信息/Info

作者:
张晓燕;陈莉明;
天津市妇女儿童保健中心健康检测中心;天津医科大学代谢病医院糖尿病肾病科;
关键词:
非酒精性脂肪性肝病非酒精性脂肪性肝炎肥胖症胰岛素抵抗儿童
摘要:
非酒精性脂肪性肝病(NAFLD)是导致儿童及青少年肝病的最常见原因。近年来,由于肥胖症的发病率逐年升高,NAFLD的患病率也明显增加。对于非酒精性脂肪性肝炎(NASH)的确诊及分级依赖于组织活检。一些非创伤性的检测指标及影像技术的发展有助于在NAFLD高风险人群中进行大范围筛查。在儿童患者中存在两种组织类型不同的NASH,其临床特征及人群特征也有差异。至今并未有儿童NAFLD的最佳治疗方案,但研究人员认为生活方式干预如饮食控制或锻炼具有一定作用。维生素E和二甲双胍对儿童NAFLD的治疗作用正处于临床研究之中。

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更新日期/Last Update: 2007-08-20