[1]张倍宁 闫如意 周金莲 崔彦.甲状腺癌中miRNA的表达及作用[J].国际内分泌代谢杂志,2018,38(03):167-170.[doi:10.3760/cma.j.issn.1673-4157.2018.03.006]
 Zhang Beining*,Yan Ruyi,Zhou Jinlian,et al.Expression and function of miRNA in thyroid carcinoma[J].International Journal of Endocrinology and Metabolism,2018,38(03):167-170.[doi:10.3760/cma.j.issn.1673-4157.2018.03.006]
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甲状腺癌中miRNA的表达及作用()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年03期
页码:
167-170
栏目:
综述
出版日期:
2018-05-20

文章信息/Info

Title:
Expression and function of miRNA in thyroid carcinoma
作者:
张倍宁 闫如意 周金莲 崔彦
100083 北京,安徽医科大学解放军第306医院临床学院普通外科(张倍宁、崔彦); 100101 北京,解放军第306医院放射科(闫如意),病理科(周金莲),普通外科(崔彦)
Author(s):
Zhang Beining* Yan Ruyi Zhou Jinlian Cui Yan.*
Department of General Surgery, The Affiliated 306 Hospital of PLA, Anhui Medical University, Beijing 100183, China
关键词:
甲状腺癌 微小RNA
Keywords:
Thyroid carcinoma MicroRNA
DOI:
10.3760/cma.j.issn.1673-4157.2018.03.006
摘要:
microRNA(miRNA)是一类进化上高度保守、细胞内源性表达的单链非编码小分子RNA,其通过与靶基因mRNA碱基互补配对,从而在转录后水平调控靶基因的表达。近年来研究发现,多种miRNA在不同类型甲状腺癌中表达异常,表明miRNA可能在甲状腺癌的发生、发展过程中有重要的作用。
Abstract:
microRNA is a class of single-stranded, non-coding small molecule RNA that is highly conserved and endogenous, which is matched to the target gene mRNA base, thus regulating the expression of the target gene at post-transcriptional levels. In recent years, several studies have found that miRNA dysregulated expressed in different types of thyroid carcinoma, and indicated that miRNA might play important roles in the occurrence and development of thyroid carcinoma.

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备注/Memo

备注/Memo:
基金项目:全军试验技术研究计划重点项目(SYFD1500128) Fund program:The Key Program Grants of PLA Planning Technology Research(SYFD1500128)
通信作者:崔彦, Email: dryancui@aliyun.com Corresponding author: Cui Yan, Email: dryancui@aliyun.com
更新日期/Last Update: 2018-03-30