[1]刘敏 王彦.1,5-脱水葡萄糖醇与糖尿病及其并发症[J].国际内分泌代谢杂志,2018,38(02):106-109.[doi:10.3760/cma.j.issn.1673-4157.2018.02.009]
　Liu Min,Wang Yan.1,5-Anhydroglucitol in diabetes and its complications[J].International Journal of Endocrinology and Metabolism,2018,38(02):106-109.[doi:10.3760/cma.j.issn.1673-4157.2018.02.009]
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1,5-脱水葡萄糖醇与糖尿病及其并发症()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
38
期数:
2018年02期
页码:
106-109
栏目:
综述
出版日期:
2018-03-20

文章信息/Info

Title:
1,5-Anhydroglucitol in diabetes and its complications
作者:
刘敏 王彦
030000 太原,山西医科大学第一医院内分泌科
Author(s):
Liu Min;  Wang Yan
Department of Endocrinology, The First Hospital, Shanxi Medical University, Taiyuan 030000,China
关键词:
1; 5-脱水葡萄糖醇;  糖尿病;  餐后高血糖;  糖尿病并发症
Keywords:
1; 5-Anhydroglucitol;  Diabetes mellitus;  Postprandial hyperglycemia;  Diabetic complications
DOI:
10.3760/cma.j.issn.1673-4157.2018.02.009
摘要:
1,5-脱水葡萄糖醇(1,5-AG)结构上类似葡萄糖,具有封闭吡喃环结构,稳定且不参与体内代谢,因尿糖竞争性抑制其重吸收而降低。1,5-AG反映短期血糖控制水平,可筛查出平均血糖控制尚可但伴有餐后高血糖(PPH)或血糖波动者,对HbA1c监测血糖作合理补充,并辅助鉴别糖尿病亚型及预测糖尿病血管并发症,有较好的临床价值。
Abstract:
1,5-anhydroglucitol(1,5-AG)is structurally similar to glucose, with a closed pyran ring structure that confers metabolic stability and does not participate in vivo metabolism, which reduces the tubular reabsorption by competitive inhibition of urine glucose. 1,5-AG reflects short-term glycemic status, detects moderately or well-controlled diabetes which is accompanied with postprandial hyperglycemia(PPH)and glucose fluctuation, and makes a reasonable supplement for HbA1c in glucose monitoring, assists identify the subtypes of diabetes and predicts diabetic vascular complications, thus has a dramatical clinical significance.

参考文献/References:


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备注/Memo

备注/Memo:

通信作者:王彦,Email:wyroad@126.com
更新日期/Last Update: 1900-01-01