[1]王滢,李倩.脑利钠肽与糖脂代谢的关系[J].国际内分泌代谢杂志,2015,(02):103-105.[doi:10.3760/cma.j.issn.1673-4157.2015.02.008]
 Wang Ying,Li Qian..Association between brain natriuretic peptide and glycolipid metabolism[J].International Journal of Endocrinology and Metabolism,2015,(02):103-105.[doi:10.3760/cma.j.issn.1673-4157.2015.02.008]
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脑利钠肽与糖脂代谢的关系()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年02
页码:
103-105
栏目:
综述
出版日期:
2015-03-20

文章信息/Info

Title:
Association between brain natriuretic peptide and glycolipid metabolism
作者:
王滢李倩
210006 南京医科大学附属南京医院(南京市第一医院)内分泌科   
Author(s):
Wang YingLi Qian.
Department of Endocrinology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006,China Corresponding author:Li Qian,Email:shygu@njmu.edu.cn
关键词:
脑利钠肽代谢综合征脂代谢糖尿病肥胖
Keywords:
Brain natriuretic peptideMetabolic syndromeLipid metabolismDiabetes mellitusObesity
DOI:
10.3760/cma.j.issn.1673-4157.2015.02.008
摘要:
脑利钠肽作为内分泌激素主要通过调节水盐平衡维持机体内环境稳态,现已被广泛用于心血管疾病的临床诊断及判断预后,而近年来的研究表明其对代谢系统也有一定影响。脑利钠肽能通过加强脂质分解与脂肪动员作用改善脂代谢,而与糖代谢的关系尚存争议。多数研究显示其与血糖水平呈负相关,这主要与增加葡萄糖利用及扩血管作用有关。故脑利钠肽在减重、预防糖尿病及代谢综合征的发展中均有一定临床应用前景。
Abstract:
Brain natriuretic peptide(BNP) is a member of the endocrine system,and it maintains homeostasis of inner environment by regulating body fluid. BNP has been widely used to identify patients at high risk for cardiovascular disease and judge the prognosis. However recent studies have indicated that BNP also had an effect on metabolic system. BNP can ameliorate lipid metabolism via activating lipolysis and improving lipid mobilization,but the relationship between BNP and glucose metabolism is still controversial. Most studies suggest that BNP is negatively associated with glucose levels,which is mainly explained by increased usage of glucose and peripheral vasodilation of BNP. So there might be therapeutic potential of BNP in treatment of obesity,diabetes and metabolic syndrome.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81200594) 通信作者:李倩,Email: shygu@njmu.edu.cn
更新日期/Last Update: 2015-03-20