[1]汤进芝,王雯,王蓉.质子泵抑制剂对糖尿病患者血糖的影响[J].国际内分泌代谢杂志,2014,(02):115-117.[doi:10.3760/cma.j.issn.1673-4157.2014.02.013]
 Tang Jinzhi,Wang Wen,W ang Rong..Effects of proton pump inhibitor on glycemic control in diabetic patients[J].International Journal of Endocrinology and Metabolism,2014,(02):115-117.[doi:10.3760/cma.j.issn.1673-4157.2014.02.013]
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质子泵抑制剂对糖尿病患者血糖的影响()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年02期
页码:
115-117
栏目:
综述
出版日期:
2014-04-30

文章信息/Info

Title:
Effects of proton pump inhibitor on glycemic control in diabetic patients
作者:
汤进芝王雯王蓉
350025 福州,安徽医科大学南京军区福州总医院临床学院,南京军区福州总医院消化内科   
Author(s):
Tang JinzhiWang Wen W ang Rong.
Anhui Medical University's Clinical College of Fuzhou General Hospital of Nanjing Command.Department of Gastroenterology,Fuzhou General Hospital of Nanjing Command,Anhui Medical University,Fuzhou 350025,China Corresponding author:Wang Wen,Email:wangw68@me
关键词:
质子泵抑制剂糖尿病胃泌素血糖糖化血红蛋白
Keywords:
Proton pump inhibitorDiabetes mellitusGastrinGlucoseGlycosylated hemoglobin
DOI:
10.3760/cma.j.issn.1673-4157.2014.02.013
摘要:
质子泵抑制剂是一种抑制胃酸分泌的药物,但临床回顾性研究发现,在糖尿病患者中,降糖药联合质子泵抑制剂治疗可明显降低血糖和糖化血红蛋白水平。动物试验也发现质子泵抑制剂能够降低糖尿病动物模型的血糖,其机制可能与质子泵抑制剂升高胃泌素水平、延缓胃排空以及生长抑素的分泌增加有关。
Abstract:
Proton pump inhibitors are drugs which could decrease the secretion of gastric acid.A few retrospective studies in diabetic patients have shown that proton pump inhibitors could decrease the level of blood glucose and HbA1c. Moreover,proton pump inhibitors have significant glucose-lowering effects in animals model of diabetes.The mechanisms may be associated with the stimulation of gastrin and somatostatin secretion and the delay of gastric emptying.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:福建省社会发展重点项目(2011Y0044) 通信作者:王雯,Email:wangw68@medmail.com.cn
更新日期/Last Update: 2014-03-20