[1]俞璐,王倩,许岚.甲皱襞毛细血管镜在糖尿病微血管并发症筛查中的应用[J].国际内分泌代谢杂志,2022,42(03):203-206.[doi:10.3760/cma.j.cn121383-20210621-06054]
 Yu Lu,Wang Qian,Xu Lan..Application of nailfold capillaroscopy in the screening of diabetic microvascular complications[J].International Journal of Endocrinology and Metabolism,2022,42(03):203-206.[doi:10.3760/cma.j.cn121383-20210621-06054]
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甲皱襞毛细血管镜在糖尿病微血管并发症筛查中的应用()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年03期
页码:
203-206
栏目:
综述
出版日期:
2022-05-20

文章信息/Info

Title:
Application of nailfold capillaroscopy in the screening of diabetic microvascular complications
作者:
俞璐王倩许岚
南京医科大学附属无锡人民医院内分泌科 214023
Author(s):
Yu Lu Wang Qian Xu Lan.
Department of Endocrinology, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China
关键词:
糖尿病 糖尿病微血管并发症 甲皱襞毛细血管镜
Keywords:
Diabetes mellitus Diabetic microvascular complications Nailfold capillaroscopy
DOI:
10.3760/cma.j.cn121383-20210621-06054
摘要:
目前临床上对糖尿病视网膜病变和糖尿病肾脏病的早期筛查手段存在一定的局限性。甲皱襞毛细血管镜是一种简便无创的在体显微成像技术,能发现早期的皮肤微血管病变。甲皱襞毛细血管镜下的皮肤微血管改变随着糖尿病、糖尿病视网膜病变及糖尿病肾脏病的发生发展而变化,因此可以将其应用于糖尿病微血管并发症的早期筛查和随访。但目前对甲皱襞毛细血管镜下糖尿病微血管并发症的图像特征的描述和评分方法尚未达成共识,需要进一步的研究和总结,有助于为糖尿病微血管并发症的诊治提供更灵敏的评估手段。
Abstract:
At present, there are limitations in clinical early screening methods for diabetic retinopathy and diabetic kidney disease. Nailfold capillaroscopy is a simple and non-invasive microscopic imaging technique that can detect early skin microvascular lesions. The skin microvascular under nailfold capillaroscopy changes with the occurrence and development of diabetes, diabetic retinopathy and diabetic kidney disease, so it can be used in the early screening and follow-up of diabetic microvascular complications. However, there is no consensus on the description and scoring method of the image features of diabetic microvascular complications under nailfold capillaoscopy yet. Further research and summary are needed to provide a more sensitive evaluation method for the diagnosis and treatment of diabetic microvascular complications.

参考文献/References:

[1] Maddaloni E,Coleman RL,Agbaje O,et al.Time-varying risk of microvascular complications in latent autoimmune diabetes of adulthood compared with type 2 diabetes in adults: a post-hoc analysis of the UK prospective diabetes study 30-year follow-up data(UKPDS 86)[J].Lancet Diabetes Endocrinol,2020,8(3):206-215.DOI:10.1016/S2213-8587(20)30003-6.
[2] Jakhar D,Grover C,Singal A.Nailfold capillaroscopy with USB dermatoscope:a cross-sectional study in healthy adults[J].Indian J Dermatol Venereol Leprol,2020,86(1):33-38.DOI:10.4103/ijdvl.IJDVL_240_18.
[3] Yuksel EP,Yuksel S,Soylu K,et al.Microvascular abnormalities in asymptomatic chronic smokers:a videocapillaroscopic study[J].Microvasc Res,2019,124:51-53.DOI:10.1016/j.mvr.2019.03.004.
[4] Bernardino V,Rodrigues A,Lladó A,et al.Nailfold capillaroscopy and autoimmune connective tissue diseases in patients from a Portuguese nailfold capillaroscopy clinic[J].Rheumatol Int,2020,40(2):295-301.DOI:10.1007/s00296-019-04427-0.
[5] Sapozhnikov M,Rehman M,Johnson C,et al.Characterization of microvascular disease in patients with sickle cell disease using nailfold capillaroscopy[J].Microvasc Res,2019,125:103877.DOI:10.1016/j.mvr.2019.04.007.
[6] Schoina M,Loutradis C,Theodorakopoulou M,et al.The presence of diabetes mellitus further impairs structural and functional capillary density in patients with chronic kidney disease[J].Microcirculation,2021,28(2):e12665.DOI:10.1111/micc.12665.
[7] Zumstein Camargo C,Kayser C.Capillaroscopy changes are associated with disease progression in patients with early systemic sclerosis:A prospective study[J].Int J Rheum Dis,2019,22(7):1319-1326.DOI:10.1111/1756-185X.13592.
[8] Meyer MF,Pfohl M,Schatz H.Correlations between morphological and functional microcirculatory alterations in diabetes and the impact of metabolic control and disease duration[J].Microvasc Res,2000,59(1):186-189.DOI:10.1006/mvre.1999.2210.
[9] Chang CH,Tsai RK,Wu WC,et al.Use of dynamic capillaroscopy for studying cutaneous microcirculation in patients with diabetes mellitus[J].Microvasc Res,1997,53(2):121-127.DOI:10.1006/mvre.1996.2003.
[10] Pazos-Moura CC,Moura EG,Bouskela E,et al.Nailfold capillaroscopy in non-insulin dependent diabetes mellitus:blood flow velocity during rest and post-occlusive reactive hyperaemia[J].Clin Physiol,1990,10(5):451-461.DOI:10.1111/j.1475-097x.1990.tb00825.x.
[11] Maldonado G,Guerrero R,Paredes C,et al.Nailfold capillaroscopy in diabetes mellitus[J].Microvasc Res,2017,112:41-46.DOI:10.1016/j.mvr.2017.03.001.
[12] Lisco G,Cicco G,Cignarelli A,et al.Computerized video-capillaroscopy alteration related to diabetes mellitus and its complications[J].Adv Exp Med Biol,2018,1072:363-368.DOI:10.1007/978-3-319-91287-5_58.
[13] Barchetta I,Riccieri V,Vasile M,et al.High prevalence of capillary abnormalities in patients with diabetes and association with retinopathy[J].Diabet Med,2011,28(9):1039-1044.DOI:10.1111/j.1464-5491.2011.03325.x.
[14] Hsu PC,Liao PY,Chang HH,et al.Nailfold capillary abnormalities are associated with type 2 diabetes progression and correlated with peripheral neuropathy[J].Medicine(Baltimore),2016,95(52):e5714.DOI:10.1097/MD.0000000000005714.
[15] Kuryliszyn-Moskal A,Zarzycki W,Dubicki A,et al.Clinical usefulness of videocapillaroscopy and selected endothelial cell activation markers in people with type 1 diabetes mellitus complicated by microangiopathy[J].Adv Med Sci,2017,62(2):368-373.DOI:10.1016/j.advms.2016.11.007.
[16] Uyar S,Balkarl A,Erol MK,et al.Assessment of the relationship between diabetic retinopathy and nailfold capillaries in type 2 diabetics with a noninvasive method:Nailfold videocapillaroscopy[J].J Diabetes Res,2016,2016:7592402.DOI:10.1155/2016/7592402.
[17] Bakirci S,Celik E,Acikgoz SB,et al.The evaluation of nailfold videocapillaroscopy findings in patients with type 2 diabetes with and without diabetic retinopathy[J].North Clin Istanb,2018,6(2):146-150.DOI:10.14744/nci.2018.02222.
[18] Shikama M,Sonoda N,Morimoto A,et al.Association of crossing capillaries in the finger nailfold with diabetic retinopathy in type 2 diabetes mellitus[J].J Diabetes Investig,2021,12(6):1007-1014.DOI:10.1111/jdi.13444.
[19] Zaugg-Vesti BR,Franzeck UK,von Ziegler C,et al.Skin capillary aneurysms detected by indocyanine green in type I diabetes with and without retinal microaneurysms[J].Int J Microcirc Clin Exp,1995,15(4):193-198.DOI:10.1159/000178975.
[20] Schoina M,Loutradis C,Memmos E,et al.Microcirculatory function deteriorates with advancing stages of chronic kidney disease independently of arterial stiffness and atherosclerosis[J].Hypertens Res,2021,44(2):179-187.DOI:10.1038/s41440-020-0525-y.
[21] Han WM,Chen XC,Li GR,et al.Acacetin protects against high glucose-induced endothelial cells injury by preserving mitochondrial function via activating Sirt1/Sirt3/AMPK signals[J].Front Pharmacol,2020,11:607796.DOI:10.3389/fphar.2020.607796.
[22] Kachamakova-Trojanowska N,Stepniewski J,Dulak J.Human iPSCs-derived endothelial cells with mutation in HNF1A as a model of maturity-onset diabetes of the young[J].Cells,2019,8(11):1440.DOI:10.3390/cells8111440.
[23] Demirseren DD,Emre S,Akoglu G,et al.Relationship between skin diseases and extracutaneous complications of diabetes mellitus:Clinical analysis of 750 patients[J].Am J Clin Dermatol,2014,15(1):65-70.DOI:10.1007/s40257-013-0048-2.
[24] Sugimoto K,Murakami H,Deguchi T,et al.Cutaneous microangiopathy in patients with type 2 diabetes:Impaired vascular endothelial growth factor expression and its correlation with neuropathy,retinopathy and nephropathy[J].J Diabetes Investig,2019,10(5):1318-1331.DOI:10.1111/jdi.13020.
[25] Jörneskog G,Brismar K,Fagrell B.Skin capillary circulation severely impaired in toes of patients with IDDM,with and without late diabetic complications[J].Diabetologia,1995,38(4):474-480.DOI:10.1007/BF00410286.
[26] Tibiriçá E,Rodrigues E,Cobas RA,et al.Endothelial function in patients with type 1 diabetes evaluated by skin capillary recruitment[J].Microvasc Res,2007,73(2):107-112.DOI:10.1016/j.mvr.2006.11.004.
[27] Irving RJ,Walker BR,Noon JP,et al.Microvascular correlates of blood pressure,plasma glucose,and insulin resistance in health[J].Cardiovasc Res,2002,53(1):271-276.DOI:10.1016/s0008-6363(01)00450-3.

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备注/Memo

备注/Memo:
通信作者:许岚,Email:xulan126@126.com
更新日期/Last Update: 2022-05-10