[1]倪文婧 徐书杭 王建华 刘超.超声引导下热消融治疗原发性甲状旁腺功能亢进症的现状和展望[J].国际内分泌代谢杂志,2022,42(04):268-271.[doi:10.3760/cma.j.cn121383-20201223-12075]
　Ni Wenjing,Xu Shuhang,Wang Jianhua,et al.Current status and prospects of ultrasound-guided thermal ablation in the treatment of primary hyperparathyroidism[J].International Journal of Endocrinology and Metabolism,2022,42(04):268-271.[doi:10.3760/cma.j.cn121383-20201223-12075]
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超声引导下热消融治疗原发性甲状旁腺功能亢进症的现状和展望()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年04期
页码:
268-271
栏目:
临床研究
出版日期:
2022-07-20

文章信息/Info

Title:
Current status and prospects of ultrasound-guided thermal ablation in the treatment of primary hyperparathyroidism
作者:
倪文婧1 徐书杭1 王建华2 刘超1
1南京中医药大学附属中西医结合医院内分泌科 210028; 2南京中医药大学附属中西医结合医院甲乳外科 210028
Author(s):
Ni Wenjing1;  Xu Shuhang1;  Wang Jianhua2;  Liu Chao1.
1Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China; 2Department of Thyroid and Breast Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China
关键词:
原发性甲状旁腺功能亢进症;  热消融;  微波消融
Keywords:
Primary hyperparathyroidism;  Thermal ablation;  Microwave ablation
DOI:
10.3760/cma.j.cn121383-20201223-12075
摘要:
原发性甲状旁腺功能亢进症(PHPT)的治疗除了传统的手术和药物之外,以微波消融、射频消融为主的热消融技术用于治疗PHPT的报道越来越多。现有临床研究表明,热消融可以显著降低PHPT患者甲状旁腺激素和血钙水平。同时,热消融治疗PHPT具有良好的安全性,少数患者出现的微小并发症,均可自行缓解。受限于临床研究的质量和数量,目前对PHPT热消融的适应证、术中管理、术后随访和疗效评价仍无统一认识。未来仍需要开展设计严谨、样本量较大的临床试验,以进一步评估热消融治疗PHPT的有效性和安全性,以提高PHPT治疗的管理质量。
Abstract:
Apart from surgery and medication as traditional therapies for primary hyperparathyroidism(PHPT), emerging studies focused on thermal ablation to treat PHPT, especially microwave ablation and radiofrequency ablation. Currently, clinical researches have proved that levels of parathyroid hormone and serum calcium significantly dived after PHPT patients received thermal ablation compared with those before treatment. Besides, the safety of thermal ablation has been clarified. A small number of patients developed minor complications that could be spontaneously relieved with time. However, limited by the quality and quantity of clinical studies, there is no consensus on the indications, peri-ablative management, post-ablative follow-up and efficacy assessment of thermal ablation in the treatment of PHPT. In the future, clinical trials with refined design and larger sample size are still needed to further evaluate the effectiveness and safety of thermal ablation for PHPT in order to improve the management quality of PHPT.

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备注/Memo

备注/Memo:
基金项目:江苏省重点研发计划(BE2020726); 江苏省卫生健康委医学科研项目(M2020102); 2021年中华国际医学交流基金会甲状腺中青年医生研究项目(BQE-JZX-202115)
通信作者:徐书杭,shuhangxu@163.com
更新日期/Last Update: 2022-06-20