[1]钟佳燏,崔蓉蓉.microRNA与肾上腺皮质肿瘤[J].国际内分泌代谢杂志,2017,37(04):277-280.
 Zhong Jiayu,Cui Rongrong..microRNA and adrenocortical tumor[J].International Journal of Endocrinology and Metabolism,2017,37(04):277-280.
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microRNA与肾上腺皮质肿瘤()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年04期
页码:
277-280
栏目:
综述
出版日期:
2017-07-20

文章信息/Info

Title:
microRNA and adrenocortical tumor
作者:
钟佳燏崔蓉蓉
410000 长沙,中南大学湘雅二医院代谢内分泌科
Author(s):
Zhong Jiayu Cui Rongrong.
Department of Endocrinology, The Second Xiangya Hospital of Central South University, Changsha 410000, China
关键词:
microRNA 肾上腺皮质肿瘤
Keywords:
microRNA Adrenocortical tumor
文献标志码:
A
摘要:
microRNA(miRNA)是一类非编码小分子RNA,通过转录后机制抑制基因表达。其表达水平的异常和肿瘤的发生、发展关系密切。许多研究表明,异常表达的miRNA影响肾上腺皮质细胞的增殖、凋亡及功能,可作为良、恶性肾上腺皮质肿瘤的生物标志物。
Abstract:
microRNAs(miRNA)are a class of small, noncoding RNAs that inhibited gene expression by post transcriptional mechanisms. The abnormal expression of miRNA have been closely associated with the tumor genesis and development. Many studies have indicated that the abnormal expression of miRNA, which can be used as biomarkers to determine the benign or malignant adrenocortical tumors, affected the proliferation, apoptosis and function of adrenal cells.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:湖南省发改委基金课题(2013 1199号); 2016年中南大学研究生自主探索创新项目(2016zzts541)
通信作者:崔蓉蓉,Email:rongrongcui530@hotmail.com
更新日期/Last Update: 2017-07-30