[1]郑仁东,刘超.碳酸锂与内分泌功能紊乱[J].国际内分泌代谢杂志,2017,37(03):186-188.[doi:10.3760/cma.j.issn.1673-4157.2017.03.011]
　Zheng Rendong,Liu Chao..Lithium and endocrine disturbances[J].International Journal of Endocrinology and Metabolism,2017,37(03):186-188.[doi:10.3760/cma.j.issn.1673-4157.2017.03.011]
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碳酸锂与内分泌功能紊乱()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年03期
页码:
186-188
栏目:
综述
出版日期:
2017-05-20

文章信息/Info

Title:
Lithium and endocrine disturbances
作者:
郑仁东; 刘超
210028 南京中医药大学附属中西医结合医院内分泌代谢病院区
Author(s):
Zheng Rendong;  Liu Chao.
Department of Endocrinology and Metabolism, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing 210028, China
关键词:
碳酸锂;  甲状腺;  甲状旁腺;  糖代谢;  尿崩症
Keywords:
Lithium;  Thyroid;  Parathyroid;  Glucose metabolism;  Diabetes insipidus
DOI:
10.3760/cma.j.issn.1673-4157.2017.03.011
摘要:
碳酸锂主要用于躁狂症、双相情感性精神障碍、抑郁症等精神性疾病的治疗。长期使用的过程中发现其能够导致内分泌功能紊乱,主要表现为甲状腺功能减退症、甲状旁腺功能亢进症与高钙血症、糖代谢异常及血糖水平升高、肾性尿崩症,以及下丘脑-垂体-肾上腺轴功能受到抑制。因此,临床使用碳酸锂的同时,还需要注意观察其对内分泌功能的影响,以避免导致内分泌功能紊乱。
Abstract:
Lithium is used for the treatment of mental illness, such as mania, bipolar disorder, depression. But it can lead to endocrine disorders including hypothyroidism, hyperparathyroid and hypercalcemia, abnormal glucose metabolism and increase of blood glucose concentration, nephrogenic diabetes insipidus and inhibition of the hypothalamic-pituitary-adrenal axis. Therefore, its effects on the endocrine function should be observed and avoid endocrine dysfunction while lithium carbonate was used in clinic.

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备注/Memo

备注/Memo:
通信作者:刘超, Email:liuchao@nfmcn.com
更新日期/Last Update: 2017-05-20