[1]黄昀 曲伸.胰高血糖素样肽-2对能量平衡及糖代谢的调节[J].国际内分泌代谢杂志,2015,(05):324-326.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.009]
　Huang Yun,Qu Shen..Regulation of glucagon-like peptide-2 on energy balance and glucose metabolism[J].International Journal of Endocrinology and Metabolism,2015,(05):324-326.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.05.009]
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胰高血糖素样肽-2对能量平衡及糖代谢的调节()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年05期
页码:
324-326
栏目:
胰高血糖素样肽专题
出版日期:
2015-09-20

文章信息/Info

Title:
Regulation of glucagon-like peptide-2 on energy balance and glucose metabolism
作者:
黄昀 曲伸
200072 上海,同济大学附属上海市第十人民医院内分泌代谢病科
Author(s):
Huang Yun;  Qu Shen.
Department of Endocrinology, Shanghai 10th People's Hospital, Tongji University, Shanghai 200072, China
关键词:
胰高血糖素样肽-2;  能量平衡;  糖代谢
Keywords:
Glucagon-like peptide-2;  Energy balance;  Glucose metabolism
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.05.009
摘要:
胰高血糖素样肽-2(GLP-2)是一种新型的肠道特异性营养因子,它主要通过GLP-2受体发挥作用。近期研究发现,GLP-2对肠道及中枢存在双重作用,可通过增强肠道营养物质吸收、抑制摄食行为、减缓胃排空、改善餐后血糖及胰岛素敏感性,调节能量平衡和维持糖代谢稳态。
Abstract:
Glucagon-like peptide-2(GLP-2)is known as a new intestinal trophic factor. The actions of GLP-2 are transduced by GLP-2 receptor. Recent researches show that GLP-2 can act on both gastrointestinal tract and central nervous system. GLP-2 can regulate energy balance and glucose homeostasis by enhancing intestinal nutrients absorption, inhibiting feeding behavior, decelerating gastric emptying, and promoting postprandial glycemic control and insulin sensitivity.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:2012年中华医学会临床医学科研专项基金(120120550355); 2012上海市卫生局申康慢病综合防治项目(SHDC12012303) 作者单位:200072 上海,同济大学附属上海市第十人民医院内分泌代谢病科 通信作者:曲伸,Email:qushencn@hotmail.com
更新日期/Last Update: 2015-09-20