[1]孙洪平,陈国芳,曹雯,等.限食疗法对心血管疾病预防及治疗的研究进展[J].国际内分泌代谢杂志,2014,(03):172-175，187.[doi:10.3760/cma.j.issn.1673-4157.2014.03.008]
　Sun Hongping,Chen Guofang,Cao Wen,et al.Effects of calorie restriction on prevention and treatment of cardiovascular diseases[J].International Journal of Endocrinology and Metabolism,2014,(03):172-175，187.[doi:10.3760/cma.j.issn.1673-4157.2014.03.008]
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限食疗法对心血管疾病预防及治疗的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年03期
页码:
172-175，187
栏目:
综述（临床研究）
出版日期:
2014-06-30

文章信息/Info

Title:
Effects of calorie restriction on prevention and treatment of cardiovascular diseases
作者:
孙洪平; 陈国芳; 曹雯; 狄红杰; 刘超
210028　南京,中国中医科学院江苏分院,南京中医药大学附属中西医结合医院内分泌代谢院区
Author(s):
Sun Hongping;  Chen Guofang; Cao Wen; Di Hongjie; Liu Chao.
Endocrine and Diabetes Center,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing University of Traditional Chinese Medicine,Jiangsu Branch of China Academy of Chinese Medical Science,Nanjing,210028,China Corresponding author：
关键词:
限食疗法; 心血管疾病; 2型糖尿病
Keywords:
Calorie restriction therapy; Cardiovascular disease; Type 2 diabetes mellitus
DOI:
10.3760/cma.j.issn.1673-4157.2014.03.008
摘要:
限食疗法被认为是延缓肥胖、糖尿病及心血管疾病等慢性疾病发生、发展最有效的非药物干预措施之一。目前研究认为,即使是短期限食,亦能安全、有效地预防及治疗心血管疾病。限食可减轻心室肥厚、降低动脉粥样硬化风险、改善心肌缺血及心功能等,其机制可能包括抑制氧化应激、减轻炎性反应、改善线粒体功能、调节心肌凋亡及自噬等。
Abstract:
Calorie restriction therapy is considered as one of the most effective non-pharmaceutical interventions to delay chronic diseases such as obesity, diabetes,cardiovascular disease and so on.Current studies suggest that even a short period of calorie restriction can prevent and even treat the cardiovascular diseases safely and effectively.Calorie restriction can reduce ventricular hypertrophy,reduce the risk of atherosclerosis,improve myocardial ischemia and even improve cardiac function. And the possible mechanisms include inhibiting oxidative stress and inflammation,improving mitochondrial function,regulating myocardial apoptosis and autophagy,etc.

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备注/Memo

备注/Memo:
通信作者：刘超,Email: liuchao@nfmcn.com
更新日期/Last Update: 2014-05-20