[1]刘静,李利平,朱超霞,等.基于FGMS评估贴敷式胰岛素泵对1型糖尿病患者血糖控制的影响[J].国际内分泌代谢杂志,2022,42(05):344-348.[doi:10.3760/cma.j.cn121383-20210414-04039]
　Liu Jing,Li Liping,Zhu Chaoxia,et al.Evaluation of the efficacy of Equil patch insulin pump on blood glucose control in patients with type 1 diabetes based on FGMS[J].International Journal of Endocrinology and Metabolism,2022,42(05):344-348.[doi:10.3760/cma.j.cn121383-20210414-04039]
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基于FGMS评估贴敷式胰岛素泵对1型糖尿病患者血糖控制的影响()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年05期
页码:
344-348
栏目:
论著
出版日期:
2022-09-20

文章信息/Info

Title:
Evaluation of the efficacy of Equil patch insulin pump on blood glucose control in patients with type 1 diabetes based on FGMS
作者:
刘静; 李利平; 朱超霞; 马瑜瑾; 姜宏卫
河南科技大学临床医学院,河南科技大学第一附属医院内分泌科,洛阳市内分泌代谢病临床医学研究中心,河南省遗传罕见病医学重点实验室,国家代谢性疾病临床医学研究中心洛阳分中心 471003
Author(s):
Liu Jing;  Li Liping;  Zhu Chaoxia;  Ma Yujin;  Jiang Hongwei.
Luoyang Sub-Center of National Clinical Research Center for Metabolic Diseases; Medical Key Laboratory of Hereditary Rare Diseases of Henan; Luoyang Clinical Medicine Research Center of Endocrine and Metabolic Diseases; Department of Endocrinology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China
关键词:
糖尿病; 1型;  贴敷式胰岛素泵;  扫描式葡萄糖监测;  血糖控制
Keywords:
Diabetes mellitus;  Type 1 patch type;  Insulin pump;  Flash glucose monitoring;  Blood glucose control
DOI:
10.3760/cma.j.cn121383-20210414-04039
摘要:
目的 应用扫描式葡萄糖监测系统(FGMS)评估贴敷式胰岛素泵对1型糖尿病(T1DM)患者血糖动态变化的影响,比较胰岛素不同注射方式对血糖控制的疗效。方法 于2019年8月至2019年12月期间河南科技大学第一附属医院入组T1DM患者,符合纳入排除标准的受试者根据所用胰岛素注射方式分别进入3组:每日多次胰岛素注射组(MDI组),传统胰岛素泵组(CSII组),Equil贴敷式胰岛素泵组(Equil组)。其中MDI、CSII组受试者胰岛素注射方式不变,Equil组受试者由MDI或CSII转为Equil贴敷式胰岛素泵治疗。共入组患者30例,均佩戴FGMS 2周,记录FGMS监测期间各项血糖指标,监测不良事件,比较各组血糖控制效果和治疗满意度。结果 两组应用胰岛素泵的患者平均血糖波动幅度(MAGE)均小于MDI组,使用贴敷式胰岛素泵的患者严重低血糖(≤2.8 mmol/L)时间少、血糖变异系数(CV)低(P均<0.05)。结论 Equil贴敷式胰岛素泵的血糖控制效果不亚于传统胰岛素泵。
Abstract:
Objective Application of flash glucose monitoring system(FGMS)to evaluate the effect of patch insulin pumps on dynamic changes of blood glucose in patients with type 1 diabetes(T1DM), and to compare the effects of different insulin injection methods on blood glucose control.Methods T1DM patients were enrolled in the First Affiliated Hospital of Henan University of Science and Technology from August to December 2019. Subjects who met the inclusion and exclusion criteria were divided into 3 groups based on their insulin injection method: multiple daily insulin injection group(MDI group), traditional insulin pump group(CSII group), and Equil patch insulin pump group(Equil group). The insulin injection method of subjects in the MDI and CSII groups remained unchanged, and the subjects in the Equil group switched from MDI or CSII to Equil treatment. A total of 30 patients were enrolled, all wearing FGMS for 2 weeks. The blood glucose indexes during FGMS monitoring and adverse events were recorded, and the blood glucose control and treatment satisfaction of each group were compared.Results The mean amplitude of glycemic excursions(MAGE)of the two groups of patients using insulin pumps was lower than that of the MDI group. Patients with patch insulin pump had fewer severe hypoglycemia(≤2.8 mmol/L)and lower blood glucose coefficient of variation(CV)(all P<0.05).Conclusion Equil patch insulin pump can control blood glucose as effectively as traditional insulin pump.

参考文献/References:

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备注/Memo

备注/Memo:
通信作者:李利平,Email: llp1203@163.com
基金项目:药品评价·微泰青年学者糖尿病技术研究基金项目(YPPJ-01-39)
更新日期/Last Update: 2022-09-10