[1]顾丹阳,邵加庆.角膜共焦显微镜检测在糖尿病微血管病变早期诊断 及评估中的作用[J].国际内分泌代谢杂志,2017,37(06):405-407.
 Gu Danyang,Shao Jiaqing..Role of corneal confocal microscopy in early diagnosis and evaluation of diabetic microvascular disease[J].International Journal of Endocrinology and Metabolism,2017,37(06):405-407.
点击复制

角膜共焦显微镜检测在糖尿病微血管病变早期诊断 及评估中的作用()
分享到:

《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年06期
页码:
405-407
栏目:
综述
出版日期:
2017-11-20

文章信息/Info

Title:
Role of corneal confocal microscopy in early diagnosis and evaluation of diabetic microvascular disease
作者:
顾丹阳邵加庆
210002 南京医科大学金陵临床医学院(解放军南京总医院)内分泌科
Author(s):
Gu Danyang Shao Jiaqing.
Department of Endocrinology, Jinling Clinical Medicine, Nanjing Medical University/Nanjing General Hospital of PLA, Nanjing 210002, China
关键词:
角膜 角膜共焦显微镜 糖尿病微血管病变
Keywords:
Cornea Corneal confocal microscopy Diabetic microvascular disease
文献标志码:
A
摘要:
顾丹阳 邵加庆
Abstract:
The early detection and evaluation of diabetic microvascular disease is very important. Cornea confocal microscopy(CCM)is a non-invasive, reiterative, rapid, in vivo clinical examination technique. It can image corneal nerve fibers structure, quantity, part of its function and plays a vital role in early diagnosis and evaluation of treatment in diabetic neuropathy. Meanwhile, in diabetic retinopathy(DR)and diabetic nephropathy(DN), it also has related application value.

参考文献/References:

[1] Papanas N, Ziegler D. Corneal confocal microscopy: a new technique for early detection of diabetic neuropathy[J].Curr Diab Rep,2013,13(4):488-499.DOI:10.1007/s11892-013-0390-z.
[2] 贾骁凡,李明顺,许菲,等.2型糖尿病患者角膜神经形态与糖尿病微血管并发症关系研究[J].中华保健医学杂志,2016,18(3):189-192.DOI:10.3969/issn.1674-3245.2016.03.004.
[3] 薛春燕,邵加庆,陆成伟,等.角膜激光共焦显微镜对糖尿病周围神经病变的早期诊断[J].中国糖尿病杂志,2010,18(9):679-681.DOI:10.3969/j.issn.1006-6187.2010.09.012.
[4] Chen X, Graham J, Dabbah MA,et al. Small nerve fiber quantification in the diagnosis of diabetic sensorimotor polyneuropathy: comparing corneal confocal microscopy with intraepidermal nerve fiber density[J].Diabetes Care,2015,38(6):1138-1144. DOI:10.2337/dc14-2422.
[5] Hertz P, Bril V, Orszag A,et al. Reproducibility of in vivo corneal confocal microscopy as a novel screening test for early diabetic sensorimotor polyneuropathy[J].Diabet Med,2011,28(10):1253-1260. DOI:10.1111/j.1464-5491.2011.03299.x.
[6] Petropoulos IN, Alam U, Fadavi H, et al. Corneal nerve loss detected with corneal confocal microscopy is symmetrical and related to the severity of diabetic polyneuropathy[J].Diabetes Care,2013,36(11):3646-3651. DOI:10.2337/dc13-0193.
[7] Jiang MS, Yuan Y, Gu ZX, et al. Corneal confocal microscopy for assessment of diabetic peripheral neuropathy: a meta-analysis[J].Br J Ophthalmol,2016,100(1):9-14. DOI:10.1136/bjophthalmol-2014-306038.
[8] Ziegler D, Papanas N, Zhivov A, et al. Early detection of nerve fiber loss by corneal confocal microscopy and skin biopsy in recently diagnosed type 2 diabetes[J].Diabetes,2014,63(7):2454-2463.DOI:10.2337/db13-1819.
[9] Lewis EJ, Perkins BA, Lovblom LE, et al. Using in vivo corneal confocal microscopy to identify diabetic sensorimotor polyneuropathy riskprofiles in patients with type 1 diabetes[J].BMJ Open Diabetes Res Care,2017,5(1):e000251. DOI:10.1136/bmjdrc-2016-000251.
[10] Azmi S, Ferdousi M, Petropoulos IN, et al. Corneal confocal microscopy shows an improvement in small-fiber neuropathy in subjects with type 1 diabetes on continuous subcutaneous insulin infusion compared with multiple dailyinjection[J].Diabetes Care,2015,38(1):e3-e4. DOI:10.2337/dc14-1698.
[11] Mehra S, Tavakoli M, Kallinikos PA,et al. Corneal confocal microscopy detects early nerve regeneration after pancreas transplantation in patients with type 1 diabetes[J].Diabetes Care,2007,30(10):2608-2612. DOI:10.2337/dc07-0870.
[12] Tavakoli M, Mitu-Pretorian M, Petropoulos IN,et al. Corneal confocal microscopy detects early nerve regeneration in diabetic neuropathy aftersimultaneous pancreas and kidney transplantation[J].Diabetes,2013,62(1):254-260. DOI:10.2337/db12-0574.
[13] Messmer EM, Schmid-Tannwald C, Zapp D,et al. In vivo confocal microscopy of corneal small fiber damage in diabetes mellitus[J].Graefes Arch Clin Exp Ophthalmol,2010,248(9):1307-1312. DOI:10.1007/s00417-010-1396-8.
[14] Nitoda E, Kallinikos P, Pallikaris A,et al. Correlation of diabetic retinopathy and corneal neuropathy using confocal microscopy[J].Curr Eye Res,2012,37(10):898-906. DOI:10.3109/02713683.2012.683507.
[15] Petropoulos IN, Green P, Chan AW,et al. Corneal confocal microscopy detects neuropathy in patients with type 1 diabetes without retinopathy or microalbuminuria[J].PLoS One,2015,10(4):e0123517. DOI:10.1371/journal.pone.0123517.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81471018)
通信作者:邵加庆,Email:shaojiaq@hotmail.com
更新日期/Last Update: 2017-11-30