[1]蔡芸莹 苏恒.1型糖尿病的非胰岛素治疗[J].国际内分泌代谢杂志,2015,(06):388-391.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.007]
 Cai Yunying,Su Heng.Noninsulin management in type 1 diabetes mellitus[J].International Journal of Endocrinology and Metabolism,2015,(06):388-391.[doi:DOI:10.3760/cma.j.issn.1673-4157.2015.06.007]
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1型糖尿病的非胰岛素治疗()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2015年06期
页码:
388-391
栏目:
临床研究
出版日期:
2015-11-20

文章信息/Info

Title:
Noninsulin management in type 1 diabetes mellitus
作者:
蔡芸莹 苏恒
650032 昆明,云南省第一人民医院内分泌科(昆明理工大学附属医院)
Author(s):
Cai Yunying Su Heng
Department of Endocrinology,The First People's Hospital of Yunnan Province, The Affliated Hospital of Kunming University of Science and Technology,Kunming 650032,China
关键词:
1型糖尿病 胰淀素 肠促胰素治疗 胰岛素样生长因子 免疫治疗
Keywords:
Type 1 diabetes mellitus Amylin Incretin-based therapies Insulin-like growth factors Immunotherapeutic agents
DOI:
DOI:10.3760/cma.j.issn.1673-4157.2015.06.007
摘要:
1型糖尿病的病理特征为胰岛素的绝对缺乏,胰岛素治疗是目前1型糖尿病治疗的基石。胰淀素、肠促胰素、自身免疫反应等因素参与了1型糖尿病的发展。1型糖尿病患者胰岛素治疗联合胰岛素增敏剂、α-糖苷酶抑制剂、胰淀素、肠促胰素及免疫抑制剂可能在降低血糖、减少胰岛素用量方面获益,但益处和风险仍需进一步研究证实。
Abstract:
The pathogenic mechanism of type 1 diabetes mellitus(T1DM)is absolute deficit of insulin, and insulin remains the cornerstone of T1DM management. Amylin, incretin and autoimmune response may play roles in the development of T1DM. Insulin sensitizing agents, α-glucosidase inhibitors, amylin, incretin-based therapies and immunotherapeutic agents adjuvant to insulin in patients with T1DM may reduce blood glucose and the dose of insulin, whereas, the benefits and risks are still under evaluation.

参考文献/References:

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备注/Memo

备注/Memo:
作者单位: 650032 昆明,云南省第一人民医院内分泌科(昆明理工大学附属医院) 通信作者:苏恒, Email:su_hen@hotmail.com
更新日期/Last Update: 2015-11-20