[1]于亚静,杨彩哲,关小宏,等.桥本甲状腺炎和甲状腺癌的关系[J].国际内分泌代谢杂志,2014,(03):200-202.[doi:10.3760/cma.j.issn.1673-4157.2014.03.016]
 Yu Yajing,Yang Caizhe,Guan Xiaohong,et al.Relationship between Hashimoto's thyroiditis and thyroid carcinoma[J].International Journal of Endocrinology and Metabolism,2014,(03):200-202.[doi:10.3760/cma.j.issn.1673-4157.2014.03.016]
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桥本甲状腺炎和甲状腺癌的关系()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年03期
页码:
200-202
栏目:
综述(基础研究)
出版日期:
2014-06-30

文章信息/Info

Title:
Relationship between Hashimoto's thyroiditis and thyroid carcinoma
作者:
于亚静杨彩哲关小宏王良宸
100142 北京,空军总医院内分泌科   
Author(s):
Yu YajingYang CaizheGuan XiaohongWang Liangchen.
Department of Endocrinology,General Hospital of the Air Force,PLA,Beijing 100142,China Corresponding author:Yang Caizhe,Email:yangcaizhe2008@163.com
关键词:
桥本甲状腺炎甲状腺癌流行病学发病机制预后
Keywords:
Hashimoto's thyroiditisThyroid carcinomaEpidemiologyPathogenesisPrognosis
DOI:
10.3760/cma.j.issn.1673-4157.2014.03.016
摘要:
近年来,桥本甲状腺炎和甲状腺癌(尤其是乳头状甲状腺癌)患病率均呈上升趋势,桥本甲状腺炎合并甲状腺癌也逐年增加。桥本甲状腺炎与甲状腺癌相关性的机制尚未明了,目前有共同病因学说、癌前病变学说、淋巴细胞浸润学说3种观点,其中共同病因包括辐射、高碘、免疫及促甲状腺激素作用等,在共同病因作用下,桥本甲状腺炎、甲状腺癌患病率均升高。一些分子在桥本甲状腺炎和甲状腺癌高表达,与甲状腺其他疾病存在表达差异,可预测桥本甲状腺炎与甲状腺癌的相关性。甲状腺癌灶周围组织淋巴细胞的浸润也可能与桥本甲状腺炎相关。
Abstract:
Recently,the prevalence of Hashimoto's thyroiditis or thyroid carcinoma (especially the thy-roid papillary carcinoma) is increasing, and more and more people are suffering from Hashimoto's thyroiditis complicated with thyroid carcinoma. The mechanism of the association between Hashimoto's thyroiditis and thyroid carcinoma is unclear,but there are many hypothesis including the common etiology,precancerous lesions,lymphocyte infiltration. The common causes include radiation,high iodine intake,immune and high thyroid stimulating hormone function. Under these common causes,the prevalence of Hashimoto's thyroiditis and thyroid cancer increases. There are common molecular biological factors between Hashimoto's thyroiditis and thyroid cancer. Expression of some moleculars in Hashimoto's thyroiditis and thyroid cancer are higher than other thyroid diseases. These molecules can predict the correlation of Hashimoto's thyroiditis and thyroid cancer. Infiltration of lymphocytes in the surrounding area of thyroid cancer tissue may imply the association of Hashimoto's thyroiditis with thyroid cancer.

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备注/Memo

备注/Memo:
通信作者:杨彩哲,Email:yangcaizhe2008@163.com
更新日期/Last Update: 2014-05-20